Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TOMM22
  • Mouse genes Tomm22
  • Rat genes Tomm22
  • Zfish genes tomm22
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tomm22

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TOMM22	IPI	UniProtKB:Q9P0U1	Human	PMID:12198123
Molecular Function	GO:0005515	protein binding	TOMM22	IPI	UniProtKB:O00170	Human	PMID:14557246
Molecular Function	GO:0005515	protein binding	TOMM22	IPI	UniProtKB:O96000	Human	PMID:14557246
Molecular Function	GO:0005515	protein binding	TOMM22	IPI	UniProtKB:P30084	Human	PMID:14557246
Molecular Function	GO:0005515	protein binding	TOMM22	IPI	UniProtKB:P0DOE7	Human	PMID:25556234
Molecular Function	GO:0005515	protein binding	TOMM22	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TOMM22	IPI	UniProtKB:P13473-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TOMM22	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TOMM22	IPI	UniProtKB:Q9Y371	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Tomm22	IPI	PR:O55125	Mouse	PMID:20497468
Molecular Function	GO:0005515	protein binding	Tomm22	IPI	RGD:1303049	Rat	PMID:11956321|RGD:1303951
Molecular Function	GO:0005515	protein binding	Tomm22	IPI	UniProtKB:P36877-2	Rat	PMID:15923182|RGD:8554174
Molecular Function	GO:0008320	protein transmembrane transporter activity	Tomm22	IMP		Rat	PMID:18687331|RGD:8554729
Cellular Component	GO:0016020	membrane	TOMM22	IDA		Human	PMID:15644312
Cellular Component	GO:0016020	membrane	TOMM22	HDA		Human	PMID:19946888
Cellular Component	GO:0005743	mitochondrial inner membrane	Tomm22	HDA		Mouse	PMID:12865426
Cellular Component	GO:0005742	mitochondrial outer membrane translocase complex	TOMM22	IDA		Human	PMID:12198123
Cellular Component	GO:0005742	mitochondrial outer membrane translocase complex	TOMM22	IDA		Human	PMID:15644312
Cellular Component	GO:0005742	mitochondrial outer membrane translocase complex	Tomm22	IDA		Rat	PMID:14985332|RGD:1303976
Cellular Component	GO:0005739	mitochondrion	TOMM22	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Tomm22	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Tomm22	IDA		Rat	PMID:14985332|RGD:1303976
Biological Process	GO:0001889	liver development	tomm22	IMP	ZFIN:ZDB-GENO-100727-9	Zfish	PMID:20483998
Biological Process	GO:0001889	liver development	tomm22	IMP	ZFIN:ZDB-MRPHLNO-100726-1	Zfish	PMID:20483998
Biological Process	GO:0043065	positive regulation of apoptotic process	Tomm22	IMP		Rat	PMID:18687331|RGD:8554729
Biological Process	GO:0051204	protein insertion into mitochondrial membrane	Tomm22	IMP		Rat	PMID:18687331|RGD:8554729
Biological Process	GO:0045040	protein insertion into mitochondrial outer membrane	TOMM22	IDA		Human	PMID:15644312
Biological Process	GO:0006626	protein targeting to mitochondrion	Tomm22	IMP		Rat	PMID:19401463|RGD:13838795

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern