Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TOM1
  • Mouse genes Tom1
  • Rat genes Tom1
  • Zfish genes tom1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tom1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030276	clathrin binding	TOM1	IDA		Human	PMID:16412388
Molecular Function	GO:0032050	clathrin heavy chain binding	TOM1	IDA		Human	PMID:14563850
Molecular Function	GO:0032050	clathrin heavy chain binding	TOM1	IDA		Human	PMID:15657082
Molecular Function	GO:0070853	myosin VI binding	TOM1	IDA		Human	PMID:23023224
Molecular Function	GO:0070853	myosin VI binding	TOM1	IDA		Human	PMID:31371777
Molecular Function	GO:0010314	phosphatidylinositol-5-phosphate binding	TOM1	IDA		Human	PMID:25588840
Molecular Function	GO:0031593	polyubiquitin modification-dependent protein binding	TOM1	IDA		Human	PMID:14563850
Molecular Function	GO:0031593	polyubiquitin modification-dependent protein binding	TOM1	IDA		Human	PMID:15047686
Molecular Function	GO:0005515	protein binding	TOM1	IPI	UniProtKB:Q9H0E2	Human	PMID:14563850
Molecular Function	GO:0005515	protein binding	TOM1	IPI	UniProtKB:O60784	Human	PMID:14613930
Molecular Function	GO:0005515	protein binding	TOM1	IPI	UniProtKB:Q7Z3T8	Human	PMID:14613930
Molecular Function	GO:0005515	protein binding	TOM1	IPI	UniProtKB:Q9H0E2	Human	PMID:15047686
Molecular Function	GO:0005515	protein binding	TOM1	IPI	UniProtKB:Q7Z3T8	Human	PMID:15657082
Molecular Function	GO:0005515	protein binding	TOM1	IPI	UniProtKB:Q9H0E2	Human	PMID:16412388
Molecular Function	GO:0005515	protein binding	TOM1	IPI	UniProtKB:O75674	Human	PMID:19798056
Molecular Function	GO:0005515	protein binding	TOM1	IPI	UniProtKB:Q6FIE9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TOM1	IPI	UniProtKB:Q9H0E2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TOM1	IPI	UniProtKB:Q9H0E2	Human	PMID:26320582
Molecular Function	GO:0005515	protein binding	TOM1	IPI	UniProtKB:Q9H0E2-1	Human	PMID:26320582
Molecular Function	GO:0005515	protein binding	TOM1	IPI	UniProtKB:P50851	Human	PMID:31263572
Molecular Function	GO:0005515	protein binding	TOM1	IPI	UniProtKB:Q9H0E2	Human	PMID:31263572
Molecular Function	GO:0005515	protein binding	TOM1	IPI	UniProtKB:Q9H0E2	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	Tom1	IPI	UniProtKB:Q9QZ06	Mouse	MGI:MGI:3843439|PMID:14563850
Molecular Function	GO:0043130	ubiquitin binding	TOM1	IDA		Human	PMID:16199040
Molecular Function	GO:0043130	ubiquitin binding	TOM1	IDA		Human	PMID:31263572
Cellular Component	GO:0005737	cytoplasm	TOM1	IDA		Human	PMID:14563850
Cellular Component	GO:0005737	cytoplasm	TOM1	IDA		Human	PMID:15047686
Cellular Component	GO:0005737	cytoplasm	TOM1	IDA		Human	PMID:16412388
Cellular Component	GO:0005829	cytosol	TOM1	IDA		Human	PMID:14613930
Cellular Component	GO:0005769	early endosome	TOM1	IDA		Human	PMID:14613930
Cellular Component	GO:0005769	early endosome	TOM1	IDA		Human	PMID:15047686
Cellular Component	GO:0005769	early endosome	TOM1	IDA		Human	PMID:25588840
Cellular Component	GO:0005769	early endosome	TOM1	IDA		Human	PMID:26320582
Cellular Component	GO:0005768	endosome	TOM1	IDA		Human	PMID:15047686
Cellular Component	GO:0005768	endosome	TOM1	IDA		Human	PMID:16412388
Cellular Component	GO:0010008	endosome membrane	TOM1	IDA		Human	PMID:23023224
Cellular Component	GO:0070062	extracellular exosome	TOM1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	TOM1	HDA		Human	PMID:23533145
Cellular Component	GO:0016020	membrane	TOM1	IDA		Human	PMID:14613930
Biological Process	GO:0061909	autophagosome-lysosome fusion	TOM1	IMP		Human	PMID:23023224
Biological Process	GO:0016197	endosomal transport	TOM1	IDA		Human	PMID:14563850
Biological Process	GO:0016197	endosomal transport	TOM1	IDA		Human	PMID:26320582
Biological Process	GO:1901098	positive regulation of autophagosome maturation	TOM1	IMP		Human	PMID:23023224
Biological Process	GO:1904978	regulation of endosome organization	TOM1	IDA		Human	PMID:25588840
Biological Process	GO:0061753	substrate localization to autophagosome	TOM1	IMP		Human	PMID:23023224

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern