Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TNNT1
  • Mouse genes Tnnt1
  • Rat genes Tnnt1
  • Zfish genes tnnt1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tnnt1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TNNT1	IPI	UniProtKB:P09493	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	TNNT1	IPI	UniProtKB:O95751	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TNNT1	IPI	UniProtKB:P09493	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TNNT1	IPI	UniProtKB:P62380	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TNNT1	IPI	UniProtKB:Q16236	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TNNT1	IPI	UniProtKB:Q5VU62	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TNNT1	IPI	UniProtKB:Q6A162	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TNNT1	IPI	UniProtKB:Q96JN2-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TNNT1	IPI	UniProtKB:Q9UBB9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TNNT1	IPI	UniProtKB:Q9UBU8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TNNT1	IPI	UniProtKB:O95751	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TNNT1	IPI	UniProtKB:Q16236	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TNNT1	IPI	UniProtKB:Q9UBB9	Human	PMID:31515488
Molecular Function	GO:0005523	tropomyosin binding	TNNT1	IMP		Human	PMID:15665378
Molecular Function	GO:0031014	troponin T binding	Tnnt1	IDA		Rat	PMID:15788488|RGD:1599482
Cellular Component	GO:0005861	troponin complex	TNNT1	IMP		Human	PMID:15665378
Cellular Component	GO:0005861	troponin complex	TNNT1	IDA		Human	PMID:18032382
Cellular Component	GO:0005861	troponin complex	Tnnt1	IDA		Rat	PMID:15788488|RGD:1599482
Cellular Component	GO:0005861	troponin complex	Tnnt1	IDA		Rat	PMID:16192301|RGD:1599030
Biological Process	GO:0045932	negative regulation of muscle contraction	TNNT1	IDA		Human	PMID:18032382
Biological Process	GO:0006937	regulation of muscle contraction	Tnnt1	IDA		Rat	PMID:16192301|RGD:1599030
Biological Process	GO:0045214	sarcomere organization	tnnt1	IMP	ZFIN:ZDB-MRPHLNO-201103-2	Zfish	PMID:31970803
Biological Process	GO:0003009	skeletal muscle contraction	TNNT1	IMP		Human	PMID:10952871
Biological Process	GO:0031444	slow-twitch skeletal muscle fiber contraction	Tnnt1	IDA		Rat	PMID:15788488|RGD:1599482
Biological Process	GO:0014883	transition between fast and slow fiber	Tnnt1	IDA		Mouse	PMID:18978355

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern