Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FPGT-TNNI3K,TNNI3K
  • Mouse genes Tnni3k
  • Rat genes Tnni3k
  • Zfish genes tnni3k
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tnni3k

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TNNI3K	IPI	UniProtKB:P19429	Human	PMID:12721663
Molecular Function	GO:0005515	protein binding	TNNI3K	IPI	UniProtKB:P30048	Human	PMID:18205602
Molecular Function	GO:0005515	protein binding	TNNI3K	IPI	UniProtKB:Q9UKT5	Human	PMID:32296183
Molecular Function	GO:0004672	protein kinase activity	TNNI3K	IDA		Human	PMID:12721663
Cellular Component	GO:0005737	cytoplasm	TNNI3K	IDA		Human	PMID:12721663
Cellular Component	GO:0005737	cytoplasm	TNNI3K	IDA		Human	PMID:18205602
Cellular Component	GO:0005634	nucleus	TNNI3K	IDA		Human	PMID:12721663
Biological Process	GO:0086069	bundle of His cell to Purkinje myocyte communication	TNNI3K	IMP		Human	PMID:23236294
Biological Process	GO:0006468	protein phosphorylation	TNNI3K	IDA		Human	PMID:12721663
Biological Process	GO:1903779	regulation of cardiac conduction	TNNI3K	IGI	UniProtKB:Q5GIG6	Human	PMID:23236294
Biological Process	GO:1903779	regulation of cardiac conduction	Tnni3k	IMP		Mouse	MGI:MGI:5474909|PMID:23236294
Biological Process	GO:0055117	regulation of cardiac muscle contraction	TNNI3K	IMP		Human	PMID:24925317
Biological Process	GO:0002027	regulation of heart rate	TNNI3K	IGI	UniProtKB:Q5GIG6	Human	PMID:23236294
Biological Process	GO:0002027	regulation of heart rate	TNNI3K	IMP		Human	PMID:24925317
Biological Process	GO:0002027	regulation of heart rate	Tnni3k	IMP		Mouse	MGI:MGI:5474909|PMID:23236294

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern