Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TNFRSF14
  • Mouse genes Tnfrsf14
  • Rat genes Tnfrsf14
  • Zfish genes si:ch211-261n11.8,si:dkey-23c22.5,si:dkey-23c22.6,tnfrsf14,zgc:153631,zgc:153759
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tnfrsf14

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019955	cytokine binding	TNFRSF14	IPI	UniProtKB:O43557	Human	PMID:27152329
Molecular Function	GO:0005515	protein binding	TNFRSF14	IPI	UniProtKB:O43557	Human	PMID:10318773
Molecular Function	GO:0005515	protein binding	TNFRSF14	IPI	UniProtKB:O95971	Human	PMID:18193050
Molecular Function	GO:0005515	protein binding	TNFRSF14	IPI	UniProtKB:Q12933	Human	PMID:19332782
Molecular Function	GO:0005515	protein binding	TNFRSF14	IPI	UniProtKB:O43557	Human	PMID:26977880
Molecular Function	GO:0005515	protein binding	TNFRSF14	IPI	UniProtKB:O95971	Human	PMID:27152329
Molecular Function	GO:0005515	protein binding	TNFRSF14	IPI	UniProtKB:Q7Z6A9	Human	PMID:27152329
Molecular Function	GO:0005515	protein binding	TNFRSF14	IPI	UniProtKB:Q96NI6	Human	PMID:27152329
Molecular Function	GO:0005515	protein binding	TNFRSF14	IPI	UniProtKB:Q3SYB3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TNFRSF14	IPI	UniProtKB:O00463	Human	PMID:9153189
Molecular Function	GO:0005515	protein binding	TNFRSF14	IPI	UniProtKB:Q12933	Human	PMID:9153189
Molecular Function	GO:0005515	protein binding	TNFRSF14	IPI	UniProtKB:Q12933-2	Human	PMID:9153189
Molecular Function	GO:0005515	protein binding	TNFRSF14	IPI	UniProtKB:O00463	Human	PMID:9162022
Molecular Function	GO:0005515	protein binding	TNFRSF14	IPI	UniProtKB:Q12933-2	Human	PMID:9162022
Molecular Function	GO:0005515	protein binding	TNFRSF14	IPI	UniProtKB:O43557	Human	PMID:9462508
Molecular Function	GO:0005515	protein binding	Tnfrsf14	IPI	PR:Q7TSA3	Mouse	PMID:15568026
Molecular Function	GO:0031625	ubiquitin protein ligase binding	TNFRSF14	IPI	UniProtKB:Q12933	Human	PMID:11279055
Cellular Component	GO:0009897	external side of plasma membrane	Tnfrsf14	IDA		Mouse	PMID:15568026
Cellular Component	GO:0005886	plasma membrane	TNFRSF14	IDA		Human	PMID:18193050
Biological Process	GO:0035739	CD4-positive, alpha-beta T cell proliferation	Tnfrsf14	IDA		Mouse	PMID:15568026
Biological Process	GO:0002367	cytokine production involved in immune response	Tnfrsf14	IMP	MGI:MGI:4940320	Mouse	PMID:21236258
Biological Process	GO:0050829	defense response to Gram-negative bacterium	Tnfrsf14	IMP	MGI:MGI:3582550	Mouse	PMID:22801499
Biological Process	GO:0050830	defense response to Gram-positive bacterium	Tnfrsf14	IMP	MGI:MGI:3582550	Mouse	PMID:22801499
Biological Process	GO:1905675	negative regulation of adaptive immune memory response	TNFRSF14	IDA		Human	PMID:18193050
Biological Process	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation	Tnfrsf14	IDA		Mouse	PMID:15568026
Biological Process	GO:0002720	positive regulation of cytokine production involved in immune response	Tnfrsf14	IMP	MGI:MGI:4940320	Mouse	PMID:21236258
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	Tnfrsf14	IDA		Mouse	PMID:15568026
Biological Process	GO:2000406	positive regulation of T cell migration	Tnfrsf14	IMP	MGI:MGI:4940320	Mouse	PMID:21236258
Biological Process	GO:0031295	T cell costimulation	TNFRSF14	IDA		Human	PMID:10754304
Biological Process	GO:0072678	T cell migration	Tnfrsf14	IMP	MGI:MGI:4940320	Mouse	PMID:21236258

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern