Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TMPRSS3
  • Mouse genes Tmprss3
  • Rat genes Tmprss3
  • Zfish genes tmprss3a,tmprss3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tmprss3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0017080	sodium channel regulator activity	TMPRSS3	IDA		Human	PMID:12393794
Cellular Component	GO:0005783	endoplasmic reticulum	TMPRSS3	HDA		Human	PMID:16780588
Cellular Component	GO:0005783	endoplasmic reticulum	Tmprss3	IDA		Mouse	MGI:MGI:5008524|PMID:21454591
Cellular Component	GO:0005789	endoplasmic reticulum membrane	TMPRSS3	IDA		Human	PMID:12393794
Cellular Component	GO:0005789	endoplasmic reticulum membrane	TMPRSS3	IDA		Human	PMID:17918732
Cellular Component	GO:0043025	neuronal cell body	Tmprss3	IDA		Mouse	MGI:MGI:5308539|PMID:17918732
Biological Process	GO:0006883	intracellular sodium ion homeostasis	TMPRSS3	IDA		Human	PMID:12393794
Biological Process	GO:0007605	sensory perception of sound	Tmprss3	IMP		Mouse	MGI:MGI:5008524|PMID:21454591
Biological Process	GO:0007605	sensory perception of sound	Tmprss3	IEP		Rat	PMID:12393794|RGD:1599442

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern