Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TMEM109
  • Mouse genes Tmem109
  • Rat genes Tmem109
  • Zfish genes si:dkey-9i23.15
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tmem109

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TMEM109	IPI	UniProtKB:O14880	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM109	IPI	UniProtKB:O43278-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM109	IPI	UniProtKB:O43315	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM109	IPI	UniProtKB:P27105	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM109	IPI	UniProtKB:P41181	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM109	IPI	UniProtKB:Q05940	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM109	IPI	UniProtKB:Q13113	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM109	IPI	UniProtKB:Q4KMG9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM109	IPI	UniProtKB:Q8NBJ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM109	IPI	UniProtKB:Q8TED1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM109	IPI	UniProtKB:Q96HE8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM109	IPI	UniProtKB:Q96K19-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM109	IPI	UniProtKB:Q9H2K0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM109	IPI	UniProtKB:Q9NR31	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM109	IPI	UniProtKB:Q9Y282	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Tmem109	IPI	UniProtKB:P02511	Mouse	PMID:23542032
Cellular Component	GO:0070062	extracellular exosome	TMEM109	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	TMEM109	HDA		Human	PMID:20458337
Biological Process	GO:0071480	cellular response to gamma radiation	TMEM109	IMP		Human	PMID:23542032
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Tmem109	IMP	MGI:MGI:4453832	Mouse	PMID:20060811
Biological Process	GO:0060548	negative regulation of cell death	TMEM109	IMP		Human	PMID:23542032

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern