Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TLK1
  • Mouse genes Tlk1
  • Rat genes Tlk1
  • Zfish genes tlk1a,tlk1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tlk1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	TLK1	IDA		Human	PMID:12660173
Molecular Function	GO:0005515	protein binding	TLK1	IPI	UniProtKB:Q5VU62	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TLK1	IPI	UniProtKB:Q9P127	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TLK1	IPI	UniProtKB:P10073	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TLK1	IPI	UniProtKB:P26367	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TLK1	IPI	UniProtKB:P50458	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TLK1	IPI	UniProtKB:Q06124-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TLK1	IPI	UniProtKB:Q12800	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TLK1	IPI	UniProtKB:Q3KNS6-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TLK1	IPI	UniProtKB:Q6PI77	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TLK1	IPI	UniProtKB:Q6PK81	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TLK1	IPI	UniProtKB:Q7L190	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TLK1	IPI	UniProtKB:Q8IY57-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TLK1	IPI	UniProtKB:Q8N720	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TLK1	IPI	UniProtKB:Q8N7W2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TLK1	IPI	UniProtKB:Q96BK5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TLK1	IPI	UniProtKB:Q96FJ2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TLK1	IPI	UniProtKB:Q96FJ2	Human	PMID:32707033
Molecular Function	GO:0004674	protein serine/threonine kinase activity	TLK1	IDA		Human	PMID:12660173
Cellular Component	GO:0005654	nucleoplasm	TLK1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	TLK1	IDA		Human	PMID:10523312
Biological Process	GO:0006886	intracellular protein transport	TLK1	IDA		Human	PMID:10588641
Biological Process	GO:0035556	intracellular signal transduction	TLK1	IDA		Human	PMID:12660173
Biological Process	GO:0006468	protein phosphorylation	TLK1	IDA		Human	PMID:12660173
Biological Process	GO:1902275	regulation of chromatin organization	TLK1	IDA		Human	PMID:12660173

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern