Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TK2
  • Mouse genes Tk2
  • Rat genes Tk2
  • Zfish genes tk2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tk2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004137	deoxycytidine kinase activity	TK2	IDA		Human	PMID:11687801
Molecular Function	GO:0004137	deoxycytidine kinase activity	TK2	IDA		Human	PMID:9989599
Molecular Function	GO:0004137	deoxycytidine kinase activity	Tk2	IDA		Mouse	MGI:MGI:1926758|PMID:11023833
Molecular Function	GO:0004137	deoxycytidine kinase activity	Tk2	IDA		Rat	PMID:21444706|RGD:5134349
Molecular Function	GO:0004797	thymidine kinase activity	TK2	IDA		Human	PMID:11687801
Molecular Function	GO:0004797	thymidine kinase activity	TK2	IDA		Human	PMID:9989599
Molecular Function	GO:0004797	thymidine kinase activity	Tk2	IDA		Mouse	MGI:MGI:1926758|PMID:11023833
Molecular Function	GO:0004797	thymidine kinase activity	Tk2	IDA		Rat	PMID:21444706|RGD:5134349
Cellular Component	GO:0005743	mitochondrial inner membrane	Tk2	HDA		Mouse	PMID:12865426
Cellular Component	GO:0005739	mitochondrion	TK2	IDA		Human	PMID:9989599
Cellular Component	GO:0005739	mitochondrion	Tk2	IDA		Mouse	MGI:MGI:1926758|PMID:11023833
Cellular Component	GO:0005739	mitochondrion	Tk2	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Tk2	IDA		Mouse	PMID:10571069
Cellular Component	GO:0005739	mitochondrion	Tk2	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Tk2	IDA		Rat	PMID:21444706|RGD:5134349
Biological Process	GO:0046092	deoxycytidine metabolic process	Tk2	IDA		Rat	PMID:21444706|RGD:5134349
Biological Process	GO:0009262	deoxyribonucleotide metabolic process	Tk2	IMP	MGI:MGI:3808750	Mouse	PMID:18467430
Biological Process	GO:0032042	mitochondrial DNA metabolic process	Tk2	IMP	MGI:MGI:3808750	Mouse	PMID:18467430
Biological Process	GO:0006264	mitochondrial DNA replication	Tk2	IMP	MGI:MGI:3802583	Mouse	PMID:18434326
Biological Process	GO:0046104	thymidine metabolic process	Tk2	IDA		Rat	PMID:21444706|RGD:5134349

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern