Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TESPA1
  • Mouse genes Tespa1
  • Rat genes
  • Zfish genes tespa1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tespa1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043274	phospholipase binding	Tespa1	IPI	UniProtKB:P19174	Mouse	PMID:28598420
Molecular Function	GO:0005515	protein binding	Tespa1	IPI	UniProtKB:Q14571	Mouse	PMID:28598420
Molecular Function	GO:0005515	protein binding	Tespa1	IPI	UniProtKB:Q14643	Mouse	PMID:28598420
Molecular Function	GO:0005515	protein binding	Tespa1	IPI	UniProtKB:Q14573	Mouse	PMID:28598420
Cellular Component	GO:0008180	COP9 signalosome	TESPA1	IDA		Human	PMID:22561606
Cellular Component	GO:0005737	cytoplasm	Tespa1	IDA		Mouse	MGI:MGI:5432321|PMID:22561606
Cellular Component	GO:0005829	cytosol	TESPA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0036398	TCR signalosome	Tespa1	IMP	MGI:5432877	Mouse	PMID:28598420
Cellular Component	GO:0036398	TCR signalosome	Tespa1	IDA		Mouse	PMID:28598420
Biological Process	GO:0010387	COP9 signalosome assembly	Tespa1	IMP		Mouse	MGI:MGI:5432321|PMID:22561606
Biological Process	GO:0033089	positive regulation of T cell differentiation in thymus	Tespa1	IMP		Mouse	MGI:MGI:5432321|PMID:22561606
Biological Process	GO:0050862	positive regulation of T cell receptor signaling pathway	Tespa1	IMP		Mouse	MGI:MGI:5432321|PMID:22561606
Biological Process	GO:0008104	protein localization	Tespa1	IMP	MGI:5432877	Mouse	PMID:28598420
Biological Process	GO:0008104	protein localization	Tespa1	IDA		Mouse	PMID:28598420
Biological Process	GO:0050856	regulation of T cell receptor signaling pathway	Tespa1	IDA		Mouse	PMID:28598420
Biological Process	GO:0050856	regulation of T cell receptor signaling pathway	Tespa1	IMP	MGI:5432877	Mouse	PMID:28598420
Biological Process	GO:0033077	T cell differentiation in thymus	Tespa1	IDA		Mouse	PMID:28598420
Biological Process	GO:0033077	T cell differentiation in thymus	Tespa1	IMP	MGI:5432877	Mouse	PMID:28598420
Biological Process	GO:0036399	TCR signalosome assembly	Tespa1	IMP	MGI:5432877	Mouse	PMID:28598420

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern