Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TESK1
  • Mouse genes Tesk1
  • Rat genes Tesk1
  • Zfish genes tesk1a,tesk1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tesk1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TESK1	IPI	UniProtKB:Q9C004	Human	PMID:12027893
Molecular Function	GO:0005515	protein binding	TESK1	IPI	UniProtKB:Q9C004	Human	PMID:15584898
Molecular Function	GO:0005515	protein binding	Tesk1	IPI	UniProtKB:P31946	Rat	PMID:11555644|RGD:631302
Molecular Function	GO:0005515	protein binding	Tesk1	IPI	UniProtKB:Q9NVD7	Rat	PMID:15817463|RGD:39458007
Molecular Function	GO:0005515	protein binding	Tesk1	IPI	UniProtKB:O43597	Rat	PMID:17974561|RGD:39458018
Molecular Function	GO:0005515	protein binding	Tesk1	IPI	UniProtKB:O43610	Rat	PMID:17974561|RGD:39458018
Molecular Function	GO:0005515	protein binding	Tesk1	IPI	UniProtKB:Q924S7	Rat	PMID:17974561|RGD:39458018
Molecular Function	GO:0005515	protein binding	Tesk1	IPI	UniProtKB:Q924S8	Rat	PMID:17974561|RGD:39458018
Molecular Function	GO:0005515	protein binding	Tesk1	IPI	UniProtKB:Q9QXV9	Rat	PMID:17974561|RGD:39458018
Molecular Function	GO:0005515	protein binding	Tesk1	IPI	UniProtKB:Q9WTP2	Rat	PMID:17974561|RGD:39458018
Molecular Function	GO:0005515	protein binding	Tesk1	IPI	UniProtKB:Q7Z699	Rat	PMID:18216281|RGD:13461749
Molecular Function	GO:0004672	protein kinase activity	TESK1	IMP		Human	PMID:15584898
Molecular Function	GO:0004672	protein kinase activity	Tesk1	IDA		Rat	PMID:11555644|RGD:631302
Molecular Function	GO:0019901	protein kinase binding	Tesk1	IPI	UniProtKB:O88664	Rat	PMID:18216281|RGD:13461749
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Tesk1	IMP		Rat	PMID:8537404|RGD:61764
Cellular Component	GO:0005813	centrosome	TESK1	IDA		Human	PMID:25849865
Cellular Component	GO:0005737	cytoplasm	TESK1	IDA		Human	PMID:15584898
Cellular Component	GO:0005737	cytoplasm	Tesk1	IDA		Rat	PMID:22302232|RGD:39458023
Cellular Component	GO:0031410	cytoplasmic vesicle	Tesk1	IDA		Rat	PMID:18216281|RGD:13461749
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Tesk1	IDA		Rat	PMID:22302232|RGD:39458023
Biological Process	GO:0051650	establishment of vesicle localization	TESK1	IMP		Human	PMID:25849865
Biological Process	GO:1902018	negative regulation of cilium assembly	TESK1	IMP		Human	PMID:25849865
Biological Process	GO:0042326	negative regulation of phosphorylation	Tesk1	IMP		Mouse	MGI:MGI:6356246|PMID:30115939
Biological Process	GO:0031953	negative regulation of protein autophosphorylation	Tesk1	IDA		Rat	PMID:18216281|RGD:13461749
Biological Process	GO:0071901	negative regulation of protein serine/threonine kinase activity	Tesk1	IDA		Rat	PMID:18216281|RGD:13461749
Biological Process	GO:0090521	podocyte cell migration	Tesk1	IMP		Mouse	MGI:MGI:6356246|PMID:30115939
Biological Process	GO:1900182	positive regulation of protein localization to nucleus	TESK1	IMP		Human	PMID:25849865
Biological Process	GO:0001934	positive regulation of protein phosphorylation	TESK1	IMP		Human	PMID:25849865
Biological Process	GO:0051496	positive regulation of stress fiber assembly	Tesk1	IDA		Rat	PMID:18216281|RGD:13461749
Biological Process	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	TESK1	IMP		Human	PMID:15584898
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	Tesk1	IMP		Mouse	MGI:MGI:6356246|PMID:30115939
Biological Process	GO:0032880	regulation of protein localization	Tesk1	IDA		Rat	PMID:18216281|RGD:13461749
Biological Process	GO:0007283	spermatogenesis	Tesk1	IEP		Rat	PMID:8537404|RGD:61764

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern