Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TCIM
  • Mouse genes Tcim
  • Rat genes Tcim
  • Zfish genes tcima,tcimb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tcim

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005112	Notch binding	TCIM	IPI	UniProtKB:Q04721	Human	PMID:25985737
Molecular Function	GO:0005515	protein binding	TCIM	IPI	UniProtKB:Q9Y3M2	Human	PMID:16424001
Cellular Component	GO:0005737	cytoplasm	TCIM	IDA		Human	PMID:16424001
Cellular Component	GO:0005737	cytoplasm	TCIM	IDA		Human	PMID:17603013
Cellular Component	GO:0005737	cytoplasm	Tcim	IDA		Mouse	PMID:24937306
Cellular Component	GO:0005829	cytosol	TCIM	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	TCIM	IDA		Human	PMID:16424001
Cellular Component	GO:0005730	nucleolus	TCIM	IDA		Human	PMID:16424001
Cellular Component	GO:0005654	nucleoplasm	TCIM	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	TCIM	IDA		Human	PMID:16424001
Cellular Component	GO:0005634	nucleus	TCIM	IDA		Human	PMID:17603013
Cellular Component	GO:0005634	nucleus	Tcim	IDA		Mouse	PMID:24937306
Cellular Component	GO:0005886	plasma membrane	TCIM	IDA		Human	GO_REF:0000052
Biological Process	GO:0034605	cellular response to heat	TCIM	IDA		Human	PMID:17603013
Biological Process	GO:0002264	endothelial cell activation involved in immune response	TCIM	IDA		Human	PMID:19684084
Biological Process	GO:0043066	negative regulation of apoptotic process	TCIM	IDA		Human	PMID:15087392
Biological Process	GO:0045746	negative regulation of Notch signaling pathway	TCIM	IDA		Human	PMID:25985737
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	TCIM	IDA		Human	PMID:19684084
Biological Process	GO:0010739	positive regulation of protein kinase A signaling	TCIM	IDA		Human	PMID:15087392
Biological Process	GO:1900020	positive regulation of protein kinase C activity	TCIM	IDA		Human	PMID:15087392
Biological Process	GO:1902806	regulation of cell cycle G1/S phase transition	TCIM	IDA		Human	PMID:18959821
Biological Process	GO:0043620	regulation of DNA-templated transcription in response to stress	TCIM	IDA		Human	PMID:17603013
Biological Process	GO:1903706	regulation of hemopoiesis	Tcim	IDA		Mouse	PMID:24937306

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern