Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TBCD
  • Mouse genes Tbcd
  • Rat genes Tbcd
  • Zfish genes tbcd
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tbcd

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0048487	beta-tubulin binding	TBCD	IDA		Human	PMID:10831612
Molecular Function	GO:0005096	GTPase activator activity	TBCD	IMP		Human	PMID:10831612
Molecular Function	GO:0005096	GTPase activator activity	TBCD	IDA		Human	PMID:20740604
Molecular Function	GO:0005515	protein binding	TBCD	IPI	UniProtKB:P36404	Human	PMID:10831612
Molecular Function	GO:0005515	protein binding	TBCD	IPI	UniProtKB:Q96AP0	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TBCD	IPI	UniProtKB:Q15813	Human	PMID:27666374
Cellular Component	GO:0005813	centrosome	TBCD	IDA		Human	PMID:27666370
Biological Process	GO:0007420	brain development	tbcd	IMP	ZFIN:ZDB-MRPHLNO-170825-3	Zfish	PMID:27807845
Biological Process	GO:0048667	cell morphogenesis involved in neuron differentiation	TBCD	IMP		Human	PMID:27666374
Biological Process	GO:0000278	mitotic cell cycle	TBCD	IMP		Human	PMID:27666370
Biological Process	GO:0031115	negative regulation of microtubule polymerization	TBCD	IDA		Human	PMID:10831612
Biological Process	GO:0031115	negative regulation of microtubule polymerization	TBCD	IDA		Human	PMID:20740604
Biological Process	GO:0007023	post-chaperonin tubulin folding pathway	TBCD	IDA		Human	PMID:11847227
Biological Process	GO:0006457	protein folding	TBCD	IDA		Human	PMID:20740604
Biological Process	GO:0010842	retina layer formation	tbcd	IMP	ZFIN:ZDB-MRPHLNO-170825-3	Zfish	PMID:27807845
Biological Process	GO:0007021	tubulin complex assembly	TBCD	IDA		Human	PMID:28158450

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern