Comparative GO Graph (mouse, human)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TAF3
  • Mouse genes Taf3
  • Rat genes
  • Zfish genes taf3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Taf3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0002039	p53 binding	Taf3	IPI	UniProtKB:P04637	Mouse	MGI:MGI:5009380|PMID:18549481
Molecular Function	GO:0005515	protein binding	TAF3	IPI	UniProtKB:P20226	Human	PMID:11438666
Molecular Function	GO:0005515	protein binding	TAF3	IPI	UniProtKB:Q12962	Human	PMID:11438666
Molecular Function	GO:0005515	protein binding	TAF3	IPI	UniProtKB:Q15543	Human	PMID:11438666
Molecular Function	GO:0005515	protein binding	TAF3	IPI	UniProtKB:Q16514	Human	PMID:11438666
Molecular Function	GO:0005515	protein binding	TAF3	IPI	UniProtKB:P52292	Human	PMID:15870280
Molecular Function	GO:0005515	protein binding	TAF3	IPI	UniProtKB:Q14974	Human	PMID:15870280
Molecular Function	GO:0005515	protein binding	TAF3	IPI	UniProtKB:P84243	Human	PMID:20953165
Molecular Function	GO:0005515	protein binding	Taf3	IPI	UniProtKB:Q6SJ95	Mouse	MGI:MGI:3773769|PMID:17704303
Molecular Function	GO:0000976	transcription cis-regulatory region binding	taf3	IPI	ZFIN:ZDB-GENE-040520-3	Zfish	PMID:19777587
Molecular Function	GO:0008134	transcription factor binding	taf3	IPI	ZFIN:ZDB-GENE-040520-3	Zfish	PMID:19777587
Molecular Function	GO:0140416	transcription regulator inhibitor activity	Taf3	IDA		Mouse	MGI:MGI:5009380|PMID:18549481
Cellular Component	GO:0001673	male germ cell nucleus	Taf3	IDA		Mouse	PMID:12665565
Cellular Component	GO:0031965	nuclear membrane	TAF3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	TAF3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	TAF3	IDA		Human	PMID:15870280
Cellular Component	GO:0005634	nucleus	TAF3	EXP		Human	PMID:23332750
Cellular Component	GO:0005669	transcription factor TFIID complex	TAF3	IPI		Human	PMID:23332750
Cellular Component	GO:0005669	transcription factor TFIID complex	TAF3	IDA		Human	PMID:11438666
Cellular Component	GO:0005669	transcription factor TFIID complex	TAF3	IDA		Human	PMID:29111974
Biological Process	GO:0030097	hemopoiesis	taf3	IMP	ZFIN:ZDB-MRPHLNO-091207-3	Zfish	PMID:19777587
Biological Process	GO:0051457	maintenance of protein location in nucleus	TAF3	IDA		Human	PMID:15870280
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	TAF3	IDA		Human	PMID:17884155
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	TAF3	IDA		Human	PMID:18549481
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	Taf3	IDA		Mouse	MGI:MGI:5009380|PMID:18549481
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	TAF3	IDA		Human	PMID:18549481
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Taf3	IDA		Mouse	MGI:MGI:5009380|PMID:18549481
Biological Process	GO:0060261	positive regulation of transcription initiation by RNA polymerase II	TAF3	IDA		Human	PMID:17884155
Biological Process	GO:0006468	protein phosphorylation	TAF3	IDA		Human	PMID:15053879
Biological Process	GO:0048634	regulation of muscle organ development	taf3	IMP	ZFIN:ZDB-MRPHLNO-091207-3	Zfish	PMID:25866244
Biological Process	GO:0051123	RNA polymerase II preinitiation complex assembly	TAF3	IPI		Human	PMID:27007846

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern