Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TACR2
  • Mouse genes Tacr2
  • Rat genes Tacr2
  • Zfish genes tacr2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tacr2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TACR2	IPI	UniProtKB:P20366:PRO_0000033530	Human	PMID:12716968
Molecular Function	GO:0005515	protein binding	TACR2	IPI	UniProtKB:P20366:PRO_0000033534	Human	PMID:12716968
Molecular Function	GO:0005515	protein binding	TACR2	IPI	UniProtKB:Q86UU9-1|UniProtKB:Q86UU9-2	Human	PMID:12716968
Molecular Function	GO:0005515	protein binding	TACR2	IPI	UniProtKB:Q99N14	Human	PMID:12716968
Molecular Function	GO:0005515	protein binding	TACR2	IPI	UniProtKB:Q9UHF0:PRO_0000033566	Human	PMID:12716968
Molecular Function	GO:0005515	protein binding	TACR2	IPI	UniProtKB:P20366:PRO_0000033534	Human	PMID:23597562
Molecular Function	GO:0016497	substance K receptor activity	Tacr2	IDA		Rat	PMID:1662278|RGD:2305982
Cellular Component	GO:0016020	membrane	Tacr2	IDA		Rat	PMID:1662278|RGD:2305982
Cellular Component	GO:0005886	plasma membrane	TACR2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0036126	sperm flagellum	TACR2	IDA		Human	PMID:17437961
Cellular Component	GO:0061827	sperm head	TACR2	IDA		Human	PMID:17437961
Cellular Component	GO:0097225	sperm midpiece	TACR2	IDA		Human	PMID:17437961
Biological Process	GO:0014827	intestine smooth muscle contraction	Tacr2	IMP		Rat	PMID:11275010|RGD:5147481
Biological Process	GO:0033685	negative regulation of luteinizing hormone secretion	Tacr2	IMP		Rat	PMID:9376629|RGD:5147487
Biological Process	GO:0035106	operant conditioning	Tacr2	IMP		Rat	PMID:17324063|RGD:2304341
Biological Process	GO:0014057	positive regulation of acetylcholine secretion, neurotransmission	Tacr2	IMP		Rat	PMID:12747940|RGD:5147477
Biological Process	GO:1902093	positive regulation of flagellated sperm motility	TACR2	IMP		Human	PMID:17437961
Biological Process	GO:0043270	positive regulation of monoatomic ion transport	Tacr2	IMP		Rat	PMID:11275010|RGD:5147481
Biological Process	GO:0070474	positive regulation of uterine smooth muscle contraction	Tacr2	IDA		Rat	PMID:12390879|RGD:2305937
Biological Process	GO:0043117	positive regulation of vascular permeability	Tacr2	IMP		Rat	PMID:9374705|RGD:5147484
Biological Process	GO:0070459	prolactin secretion	Tacr2	IMP		Rat	PMID:9376629|RGD:5147487
Biological Process	GO:0070472	regulation of uterine smooth muscle contraction	Tacr2	IDA		Mouse	MGI:MGI:5619483|PMID:15647454
Biological Process	GO:0051602	response to electrical stimulus	Tacr2	IEP		Rat	PMID:18440496|RGD:2304269

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern