Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TAB1
  • Mouse genes Tab1
  • Rat genes Tab1
  • Zfish genes tab1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tab1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019209	kinase activator activity	Tab1	IMP	MGI:MGI:2667182	Mouse	PMID:12464436
Molecular Function	GO:0048273	mitogen-activated protein kinase p38 binding	Tab1	IPI	RGD:70496	Rat	PMID:21607062|RGD:5508182
Molecular Function	GO:0005515	protein binding	TAB1	IPI	UniProtKB:Q9Y4K3	Human	PMID:10094049
Molecular Function	GO:0005515	protein binding	TAB1	IPI	UniProtKB:O43318	Human	PMID:11460167
Molecular Function	GO:0005515	protein binding	TAB1	IPI	UniProtKB:P98170	Human	PMID:11865055
Molecular Function	GO:0005515	protein binding	TAB1	IPI	UniProtKB:Q13075	Human	PMID:11865055
Molecular Function	GO:0005515	protein binding	TAB1	IPI	UniProtKB:Q96CA5	Human	PMID:11865055
Molecular Function	GO:0005515	protein binding	TAB1	IPI	UniProtKB:O43318-2	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	TAB1	IPI	UniProtKB:Q9NYJ8	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	TAB1	IPI	UniProtKB:O43318	Human	PMID:16845370
Molecular Function	GO:0005515	protein binding	TAB1	IPI	UniProtKB:Q9NYJ8	Human	PMID:16845370
Molecular Function	GO:0005515	protein binding	TAB1	IPI	UniProtKB:O43318-2	Human	PMID:19026643
Molecular Function	GO:0005515	protein binding	TAB1	IPI	UniProtKB:Q9NYJ8	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	TAB1	IPI	UniProtKB:Q9NYJ8	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	TAB1	IPI	UniProtKB:O43318	Human	PMID:22158122
Molecular Function	GO:0005515	protein binding	TAB1	IPI	UniProtKB:P98170	Human	PMID:23818254
Molecular Function	GO:0005515	protein binding	TAB1	IPI	UniProtKB:P00533	Human	PMID:24658140
Molecular Function	GO:0005515	protein binding	TAB1	IPI	UniProtKB:O43318	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	TAB1	IPI	UniProtKB:Q9NYJ8	Human	PMID:25260751
Molecular Function	GO:0005515	protein binding	TAB1	IPI	UniProtKB:P98170	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	TAB1	IPI	UniProtKB:O15294	Human	PMID:27505673
Molecular Function	GO:0005515	protein binding	TAB1	IPI	UniProtKB:O43318	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	TAB1	IPI	UniProtKB:Q9NYJ8	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	TAB1	IPI	UniProtKB:P00533	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	TAB1	IPI	UniProtKB:P47929	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TAB1	IPI	UniProtKB:O43318	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	TAB1	IPI	UniProtKB:P0DTD1:PRO_0000449623	Human	PMID:33372854
Molecular Function	GO:0005515	protein binding	TAB1	IPI	UniProtKB:P00533	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	Tab1	IPI	UniProtKB:Q62073	Mouse	MGI:MGI:5512957|PMID:19026643
Molecular Function	GO:0005515	protein binding	Tab1	IPI	UniProtKB:Q62073	Mouse	MGI:MGI:4839696|PMID:20813258
Molecular Function	GO:0005515	protein binding	Tab1	IPI	UniProtKB:Q9QYH6	Mouse	MGI:MGI:3848096|PMID:19268530
Molecular Function	GO:0005515	protein binding	Tab1	IPI	UniProtKB:Q86Y07-1	Mouse	MGI:MGI:3843421|PMID:17709393
Molecular Function	GO:0005515	protein binding	Tab1	IPI	UniProtKB:P53349	Mouse	MGI:MGI:5607447|PMID:25260751
Molecular Function	GO:0005515	protein binding	Tab1	IPI	RGD:621842	Rat	PMID:16617054|RGD:1582382
Molecular Function	GO:0044877	protein-containing complex binding	Tab1	IPI	RGD:3852|RGD:727803	Rat	PMID:16617054|RGD:1582382
Cellular Component	GO:0005829	cytosol	TAB1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	TAB1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0032991	protein-containing complex	Tab1	IDA		Rat	PMID:16617054|RGD:1582382
Biological Process	GO:0035904	aorta development	Tab1	IMP		Mouse	PMID:25807483
Biological Process	GO:0003279	cardiac septum development	Tab1	IMP		Mouse	PMID:25807483
Biological Process	GO:0060976	coronary vasculature development	Tab1	IMP		Mouse	PMID:25807483
Biological Process	GO:0003007	heart morphogenesis	Tab1	IMP	MGI:MGI:2667182	Mouse	PMID:12464436
Biological Process	GO:0001701	in utero embryonic development	Tab1	IMP	MGI:MGI:2667182	Mouse	PMID:12464436
Biological Process	GO:0030324	lung development	Tab1	IMP	MGI:MGI:2667182	Mouse	PMID:12464436
Biological Process	GO:0043406	positive regulation of MAP kinase activity	Tab1	IMP		Rat	PMID:21607062|RGD:5508182
Biological Process	GO:0043410	positive regulation of MAPK cascade	Tab1	IMP	MGI:MGI:2667182	Mouse	PMID:12464436
Biological Process	GO:0071902	positive regulation of protein serine/threonine kinase activity	TAB1	IDA		Human	PMID:11865055
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Tab1	IMP	MGI:MGI:2667182	Mouse	PMID:12464436

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern