Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SYNM
  • Mouse genes Synm
  • Rat genes Synm
  • Zfish genes synm
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Synm

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019215	intermediate filament binding	Synm	IDA		Mouse	MGI:MGI:3054589|PMID:15265691
Molecular Function	GO:0005515	protein binding	SYNM	IPI	UniProtKB:P17661	Human	PMID:11353857
Molecular Function	GO:0005515	protein binding	SYNM	IPI	UniProtKB:Q9Y4J8	Human	PMID:11353857
Molecular Function	GO:0005515	protein binding	SYNM	IPI	UniProtKB:P11532	Human	PMID:16777071
Molecular Function	GO:0005515	protein binding	SYNM	IPI	UniProtKB:P46939	Human	PMID:16777071
Molecular Function	GO:0005515	protein binding	SYNM	IPI	UniProtKB:P18206	Human	PMID:18028034
Molecular Function	GO:0005515	protein binding	SYNM	IPI	UniProtKB:Q9Y490	Human	PMID:18342854
Molecular Function	GO:0005515	protein binding	SYNM	IPI	UniProtKB:Q8WZ42	Human	PMID:25447537
Molecular Function	GO:0005515	protein binding	Synm	IPI	UniProtKB:P03995|UniProtKB:P20152	Mouse	MGI:MGI:3713044|PMID:17356066
Molecular Function	GO:0005515	protein binding	Synm	IPI	UniProtKB:A2ASS6	Mouse	MGI:MGI:5610068|PMID:25447537
Molecular Function	GO:0005200	structural constituent of cytoskeleton	SYNM	IDA		Human	PMID:11737198
Molecular Function	GO:0005200	structural constituent of cytoskeleton	SYNM	IDA		Human	PMID:16777071
Molecular Function	GO:0008307	structural constituent of muscle	SYNM	IDA		Human	PMID:11737198
Molecular Function	GO:0017166	vinculin binding	SYNM	IDA		Human	PMID:18028034
Cellular Component	GO:0043034	costamere	SYNM	IDA		Human	PMID:16777071
Cellular Component	GO:0043034	costamere	SYNM	IDA		Human	PMID:18342854
Cellular Component	GO:0005882	intermediate filament	SYNM	IDA		Human	PMID:11737198
Cellular Component	GO:0005882	intermediate filament	Synm	IDA		Rat	PMID:11353857|RGD:1302391
Cellular Component	GO:0045111	intermediate filament cytoskeleton	SYNM	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	Synm	IDA		Mouse	PMID:16817202
Cellular Component	GO:0060053	neurofilament cytoskeleton	Synm	IDA		Mouse	PMID:16817202
Cellular Component	GO:0042383	sarcolemma	Synm	IDA		Mouse	PMID:25567810
Biological Process	GO:0031443	fast-twitch skeletal muscle fiber contraction	Synm	IMP	MGI:MGI:5548847	Mouse	PMID:25567810

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern