Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SV2B
  • Mouse genes Sv2b
  • Rat genes Sv2b
  • Zfish genes sv2ba,sv2bb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sv2b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SV2B	IPI	UniProtKB:Q96LI6	Human	PMID:25416956
Cellular Component	GO:0098978	glutamatergic synapse	Sv2b	IDA		Rat	PMID:22275882|RGD:155230748
Cellular Component	GO:0016020	membrane	Sv2b	IDA		Rat	PMID:7681585|RGD:634183
Cellular Component	GO:0008021	synaptic vesicle	Sv2b	IDA		Mouse	PMID:12687700
Cellular Component	GO:0008021	synaptic vesicle	Sv2b	IDA		Rat	PMID:7681585|RGD:634183
Cellular Component	GO:0030672	synaptic vesicle membrane	Sv2b	IDA		Rat	PMID:22275882|RGD:155230748
Cellular Component	GO:0030672	synaptic vesicle membrane	Sv2b	EXP		Rat	PMID:23622064|RGD:13702180
Cellular Component	GO:0030672	synaptic vesicle membrane	Sv2b	IDA		Rat	PMID:23622064|RGD:13702180
Cellular Component	GO:0043195	terminal bouton	Sv2b	HDA		Rat	PMID:24876496|RGD:10047219
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	Sv2b	IDA		Mouse	PMID:20620874
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	Sv2b	IMP		Mouse	PMID:20620874
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	Sv2b	IDA		Mouse	PMID:20620874
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	Sv2b	IMP		Mouse	PMID:20620874

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern