Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SUCNR1
  • Mouse genes Sucnr1
  • Rat genes Sucnr1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sucnr1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SUCNR1	IPI	UniProtKB:Q9NUH8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SUCNR1	IPI	UniProtKB:P13473-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SUCNR1	IPI	UniProtKB:Q9Y371	Human	PMID:32814053
Molecular Function	GO:0038023	signaling receptor activity	Sucnr1	IDA		Mouse	PMID:27481132
Cellular Component	GO:0070062	extracellular exosome	SUCNR1	HDA		Human	PMID:19056867
Biological Process	GO:0042593	glucose homeostasis	Sucnr1	IMP	MGI:MGI:3828087	Mouse	PMID:28382382
Biological Process	GO:0032611	interleukin-1 beta production	Sucnr1	IMP	MGI:MGI:3828087	Mouse	PMID:27481132
Biological Process	GO:0002281	macrophage activation involved in immune response	Sucnr1	IMP	MGI:MGI:3828087	Mouse	PMID:27481132
Biological Process	GO:0010934	macrophage cytokine production	Sucnr1	IMP	MGI:MGI:3828087	Mouse	PMID:27481132
Biological Process	GO:0050921	positive regulation of chemotaxis	Sucnr1	IMP	MGI:MGI:3828087	Mouse	PMID:28382382
Biological Process	GO:0050729	positive regulation of inflammatory response	Sucnr1	IMP	MGI:MGI:3828087	Mouse	PMID:28382382
Biological Process	GO:0060177	regulation of angiotensin metabolic process	Sucnr1	IMP	MGI:MGI:3528754	Mouse	PMID:18535668
Biological Process	GO:0002001	renin secretion into blood stream	Sucnr1	IMP	MGI:MGI:3528754	Mouse	PMID:18535668
Biological Process	GO:0051592	response to calcium ion	Sucnr1	IMP	MGI:MGI:3528754	Mouse	PMID:18535668

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern