Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes STEAP4
  • Mouse genes Steap4
  • Rat genes Steap4
  • Zfish genes steap4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Steap4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008823	cupric reductase activity	Steap4	IDA		Mouse	PMID:16609065
Molecular Function	GO:0009055	electron transfer activity	STEAP4	IDA		Human	PMID:30337524
Molecular Function	GO:0071949	FAD binding	STEAP4	IDA		Human	PMID:30337524
Molecular Function	GO:0052851	ferric-chelate reductase (NADPH) activity	STEAP4	IDA		Human	PMID:30337524
Molecular Function	GO:0052851	ferric-chelate reductase (NADPH) activity	Steap4	IDA		Mouse	PMID:16609065
Molecular Function	GO:0020037	heme binding	STEAP4	IDA		Human	PMID:30337524
Cellular Component	GO:0005768	endosome	Steap4	IDA		Mouse	PMID:16609065
Cellular Component	GO:0070062	extracellular exosome	STEAP4	HDA		Human	PMID:23533145
Cellular Component	GO:0016020	membrane	STEAP4	IDA		Human	PMID:30337524
Cellular Component	GO:0005654	nucleoplasm	STEAP4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	STEAP4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Steap4	IDA		Mouse	MGI:MGI:2150516|PMID:11443137
Cellular Component	GO:0005886	plasma membrane	Steap4	IDA		Mouse	PMID:16609065
Biological Process	GO:0015677	copper ion import	Steap4	IDA		Mouse	PMID:16609065
Biological Process	GO:0045444	fat cell differentiation	Steap4	IEP		Mouse	MGI:MGI:2150516|PMID:11443137
Biological Process	GO:0033212	iron import into cell	Steap4	IDA		Mouse	PMID:16609065
Biological Process	GO:0098706	iron ion import across cell outer membrane	Steap4	IDA		Mouse	PMID:16609065
Biological Process	GO:0070207	protein homotrimerization	STEAP4	IDA		Human	PMID:30337524

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern