Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes STEAP3
  • Mouse genes Steap3
  • Rat genes Steap3
  • Zfish genes steap3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Steap3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008823	cupric reductase activity	Steap3	IDA		Mouse	PMID:16609065
Molecular Function	GO:0052851	ferric-chelate reductase (NADPH) activity	Steap3	IDA		Mouse	PMID:16609065
Molecular Function	GO:0052851	ferric-chelate reductase (NADPH) activity	Steap3	IMP	MGI:MGI:3758911	Mouse	PMID:18955558
Molecular Function	GO:0000293	ferric-chelate reductase activity	Steap3	IMP		Mouse	PMID:16227996
Molecular Function	GO:0000293	ferric-chelate reductase activity	Steap3	IDA		Mouse	PMID:16227996
Molecular Function	GO:0005515	protein binding	STEAP3	IPI	UniProtKB:Q8TEB9-1	Human	PMID:22624035
Molecular Function	GO:0005515	protein binding	Steap3	IPI	UniProtKB:P02786	Mouse	MGI:MGI:5775517|PMID:26642240
Cellular Component	GO:0005737	cytoplasm	STEAP3	IDA		Human	PMID:25468996
Cellular Component	GO:0005768	endosome	Steap3	IDA		Mouse	PMID:16227996
Cellular Component	GO:0005771	multivesicular body	STEAP3	IDA		Human	PMID:15319436
Cellular Component	GO:0005886	plasma membrane	Steap3	IDA		Mouse	PMID:16227996
Cellular Component	GO:0005886	plasma membrane	Steap3	IDA		Mouse	PMID:18955558
Biological Process	GO:0015677	copper ion import	Steap3	IMP	MGI:MGI:3758911	Mouse	PMID:18955558
Biological Process	GO:0015677	copper ion import	Steap3	IDA		Mouse	PMID:16609065
Biological Process	GO:0051649	establishment of localization in cell	Steap3	IMP	MGI:MGI:3609928	Mouse	PMID:16227996
Biological Process	GO:1990182	exosomal secretion	Steap3	IMP	MGI:MGI:4398911	Mouse	PMID:18617898
Biological Process	GO:0033212	iron import into cell	Steap3	IDA		Mouse	PMID:16609065
Biological Process	GO:0098706	iron ion import across cell outer membrane	Steap3	IMP	MGI:MGI:3758911	Mouse	PMID:18955558
Biological Process	GO:0098706	iron ion import across cell outer membrane	Steap3	IDA		Mouse	PMID:16609065
Biological Process	GO:0006826	iron ion transport	Steap3	IMP	MGI:MGI:3609928	Mouse	PMID:16227996
Biological Process	GO:0043065	positive regulation of apoptotic process	Steap3	IDA		Rat	PMID:10969787|RGD:1299525
Biological Process	GO:1902167	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Steap3	IMP	MGI:MGI:4398911	Mouse	PMID:18617898
Biological Process	GO:0009306	protein secretion	STEAP3	IDA		Human	PMID:15319436
Biological Process	GO:0009306	protein secretion	STEAP3	IMP		Human	PMID:22624035

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern