Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ST6GAL1
  • Mouse genes St6gal1
  • Rat genes St6gal1
  • Zfish genes st6gal1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set St6gal1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003835	beta-galactoside alpha-2,6-sialyltransferase activity	ST6GAL1	IDA		Human	PMID:23999306
Molecular Function	GO:0003835	beta-galactoside alpha-2,6-sialyltransferase activity	St6gal1	IDA		Mouse	MGI:MGI:6213409|PMID:22039275
Molecular Function	GO:0003835	beta-galactoside alpha-2,6-sialyltransferase activity	St6gal1	IMP	MGI:MGI:2387745	Mouse	PMID:12068010
Molecular Function	GO:0005515	protein binding	ST6GAL1	IPI	UniProtKB:P0C045	Human	PMID:16237761
Molecular Function	GO:0042803	protein homodimerization activity	ST6GAL1	IDA		Human	PMID:20378551
Molecular Function	GO:0008373	sialyltransferase activity	ST6GAL1	IDA		Human	PMID:21081508
Molecular Function	GO:0008373	sialyltransferase activity	St6gal1	IDA		Mouse	PMID:12966079
Molecular Function	GO:0008373	sialyltransferase activity	St6gal1	IDA		Rat	PMID:12626411|RGD:10043130
Cellular Component	GO:0005783	endoplasmic reticulum	St6gal1	IDA		Rat	PMID:12626411|RGD:10043130
Cellular Component	GO:0005797	Golgi medial cisterna	St6gal1	IDA		Rat	PMID:12626411|RGD:10043130
Cellular Component	GO:0000139	Golgi membrane	ST6GAL1	IDA		Human	PMID:20378551
Cellular Component	GO:0000138	Golgi trans cisterna	St6gal1	IDA		Rat	PMID:12626411|RGD:10043130
Biological Process	GO:0006054	N-acetylneuraminate metabolic process	ST6GAL1	IDA		Human	PMID:23999306
Biological Process	GO:0050922	negative regulation of chemotaxis	St6gal1	IDA		Rat	PMID:11559557|RGD:10043143
Biological Process	GO:2000110	negative regulation of macrophage apoptotic process	St6gal1	IDA		Rat	PMID:21930713|RGD:10043116
Biological Process	GO:0032946	positive regulation of mononuclear cell proliferation	St6gal1	IDA		Rat	PMID:21930713|RGD:10043116
Biological Process	GO:0006486	protein glycosylation	St6gal1	IMP	MGI:MGI:2387745	Mouse	PMID:12068010
Biological Process	GO:0018279	protein N-linked glycosylation via asparagine	ST6GAL1	IDA		Human	PMID:23999306
Biological Process	GO:0018279	protein N-linked glycosylation via asparagine	St6gal1	IDA		Mouse	MGI:MGI:6213409|PMID:22039275
Biological Process	GO:1990743	protein sialylation	St6gal1	IDA		Rat	PMID:21930713|RGD:10043116
Biological Process	GO:1900024	regulation of substrate adhesion-dependent cell spreading	St6gal1	IDA		Rat	PMID:11559557|RGD:10043143
Biological Process	GO:0045471	response to ethanol	St6gal1	IEP		Rat	PMID:9046376|RGD:10043140
Biological Process	GO:0097503	sialylation	ST6GAL1	IDA		Human	PMID:23999306
Biological Process	GO:0097503	sialylation	St6gal1	IDA		Mouse	MGI:MGI:2677197|PMID:12966079

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern