Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SSTR5
  • Mouse genes Sstr5
  • Rat genes Sstr5
  • Zfish genes sstr5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sstr5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SSTR5	IPI	UniProtKB:P30872	Human	PMID:15247250
Molecular Function	GO:0005515	protein binding	SSTR5	IPI	UniProtKB:P30874	Human	PMID:18653781
Molecular Function	GO:0005515	protein binding	SSTR5	IPI	UniProtKB:P31391	Human	PMID:19426801
Molecular Function	GO:0005515	protein binding	Sstr5	IPI	PR:Q8VDZ4	Mouse	PMID:21820437
Molecular Function	GO:0004994	somatostatin receptor activity	Sstr5	IDA		Rat	PMID:1362243|RGD:727545
Cellular Component	GO:0005737	cytoplasm	Sstr5	IDA		Rat	PMID:9322965|RGD:2325006
Cellular Component	GO:0005886	plasma membrane	SSTR5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Sstr5	IDA		Mouse	PMID:21820437
Cellular Component	GO:0005886	plasma membrane	Sstr5	IDA		Rat	PMID:9322965|RGD:2325006
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	Sstr5	IDA		Rat	PMID:1362243|RGD:727545
Biological Process	GO:0071385	cellular response to glucocorticoid stimulus	Sstr5	IEP		Rat	PMID:14512709|RGD:2325001
Biological Process	GO:0042593	glucose homeostasis	Sstr5	IMP	MGI:MGI:3584184	Mouse	PMID:15919085
Biological Process	GO:0032467	positive regulation of cytokinesis	SSTR5	IMP		Human	PMID:22888021
Biological Process	GO:0050796	regulation of insulin secretion	Sstr5	IMP	MGI:MGI:3584184	Mouse	PMID:15919085

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern