Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPTAN1
  • Mouse genes Sptan1
  • Rat genes Sptan1
  • Zfish genes sptan1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sptan1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	SPTAN1	HDA		Human	PMID:25468996
Molecular Function	GO:0005515	protein binding	SPTAN1	IPI	UniProtKB:Q92889	Human	PMID:12571280
Molecular Function	GO:0005515	protein binding	SPTAN1	IPI	UniProtKB:Q01082	Human	PMID:12820899
Molecular Function	GO:0005515	protein binding	SPTAN1	IPI	UniProtKB:P50402	Human	PMID:15328537
Molecular Function	GO:0005515	protein binding	SPTAN1	IPI	UniProtKB:Q9UI08	Human	PMID:16336193
Molecular Function	GO:0005515	protein binding	SPTAN1	IPI	UniProtKB:Q9NRI5	Human	PMID:17043677
Molecular Function	GO:0005515	protein binding	SPTAN1	IPI	UniProtKB:O15287	Human	PMID:19102630
Molecular Function	GO:0005515	protein binding	SPTAN1	IPI	UniProtKB:P40692	Human	PMID:20706999
Molecular Function	GO:0005515	protein binding	SPTAN1	IPI	UniProtKB:Q9NRI5	Human	PMID:29961565
Molecular Function	GO:0005515	protein binding	SPTAN1	IPI	UniProtKB:Q01082	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	SPTAN1	IPI	UniProtKB:Q9NRI5	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	Sptan1	IPI	PR:Q9QUQ5	Mouse	PMID:18796539
Molecular Function	GO:0005515	protein binding	Sptan1	IPI	PR:P39053	Mouse	PMID:23746204
Molecular Function	GO:0005515	protein binding	Sptan1	IPI	RGD:1564762	Rat	PMID:11274145|RGD:11252102
Molecular Function	GO:0005515	protein binding	Sptan1	IPI	RGD:621011	Rat	PMID:11509555|RGD:628460
Molecular Function	GO:0005515	protein binding	Sptan1	IPI	RGD:69264	Rat	PMID:11509555|RGD:628460
Molecular Function	GO:0005515	protein binding	Sptan1	IPI	UniProtKB:Q9R044	Rat	PMID:15994232|RGD:8553727
Molecular Function	GO:0044877	protein-containing complex binding	Sptan1	IPI	RGD:620460	Rat	PMID:15331416|RGD:1600864
Molecular Function	GO:0030507	spectrin binding	Sptan1	IDA		Mouse	PMID:18796539
Molecular Function	GO:0030507	spectrin binding	Sptan1	IPI	MGI:MGI:2685200	Mouse	PMID:18796539
Molecular Function	GO:0030507	spectrin binding	Sptan1	IDA		Rat	PMID:23704327|RGD:8553853
Molecular Function	GO:0019905	syntaxin binding	Sptan1	IPI	RGD:621019	Rat	PMID:16870704|RGD:2306291
Cellular Component	GO:0030863	cortical cytoskeleton	Sptan1	IDA		Mouse	PMID:18723693
Cellular Component	GO:0032437	cuticular plate	Sptan1	IDA		Mouse	PMID:18796539
Cellular Component	GO:0070062	extracellular exosome	SPTAN1	HDA		Human	PMID:20458337
Cellular Component	GO:1903561	extracellular vesicle	SPTAN1	HDA		Human	PMID:24769233
Cellular Component	GO:0005916	fascia adherens	Sptan1	IDA		Mouse	PMID:16481394
Cellular Component	GO:0098978	glutamatergic synapse	Sptan1	IDA		Rat	PMID:11454415|RGD:155230707
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	SPTAN1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016328	lateral plasma membrane	Sptan1	IDA		Mouse	PMID:18796539
Cellular Component	GO:0016020	membrane	Sptan1	IDA		Mouse	PMID:18723693
Cellular Component	GO:0015630	microtubule cytoskeleton	SPTAN1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043209	myelin sheath	Sptan1	HDA		Mouse	MGI:MGI:3834050|PMID:17634366
Cellular Component	GO:0033268	node of Ranvier	sptan1	IDA		Zfish	PMID:17331725
Cellular Component	GO:0033010	paranodal junction	Sptan1	IDA		Mouse	PMID:16687515
Cellular Component	GO:0033270	paranode region of axon	Sptan1	IDA		Mouse	MGI:MGI:3621602|PMID:16551741
Cellular Component	GO:0033270	paranode region of axon	sptan1	IDA		Zfish	PMID:17331725
Cellular Component	GO:0005886	plasma membrane	Sptan1	IDA		Rat	PMID:16870704|RGD:2306291
Cellular Component	GO:0098794	postsynapse	Sptan1	IDA		Rat	PMID:11454415|RGD:155230707
Cellular Component	GO:0032991	protein-containing complex	Sptan1	IDA		Rat	PMID:15331416|RGD:1600864
Cellular Component	GO:0032991	protein-containing complex	Sptan1	IDA		Rat	PMID:15823548|RGD:1600561
Cellular Component	GO:0030018	Z disc	Sptan1	IDA		Mouse	PMID:15247274
Biological Process	GO:0031532	actin cytoskeleton reorganization	Sptan1	IMP		Rat	PMID:16870704|RGD:2306291
Biological Process	GO:0045162	clustering of voltage-gated sodium channels	sptan1	IMP	ZFIN:ZDB-GENO-070601-1	Zfish	PMID:17331725
Biological Process	GO:0022011	myelination in peripheral nervous system	sptan1	IMP	ZFIN:ZDB-GENO-070601-1	Zfish	PMID:21518878

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern