Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPO11
  • Mouse genes Spo11
  • Rat genes Spo11
  • Zfish genes spo11
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Spo11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SPO11	IPI	UniProtKB:Q5Q0E6	Human	PMID:26917763
Molecular Function	GO:0005515	protein binding	Spo11	IPI	UniProtKB:J3QMY9	Mouse	MGI:MGI:5752405|PMID:26917764
Cellular Component	GO:0000781	chromosome, telomeric region	Spo11	IDA		Mouse	PMID:20336070
Biological Process	GO:0070192	chromosome organization involved in meiotic cell cycle	spo11	IMP	ZFIN:ZDB-GENO-190919-37	Zfish	PMID:30653507
Biological Process	GO:1990918	double-strand break repair involved in meiotic recombination	Spo11	IGI	MGI:MGI:3045334	Mouse	PMID:27760146
Biological Process	GO:0007129	homologous chromosome pairing at meiosis	Spo11	IMP	MGI:MGI:3027823	Mouse	PMID:18694567
Biological Process	GO:0007129	homologous chromosome pairing at meiosis	Spo11	IMP	MGI:MGI:2178805	Mouse	PMID:24589552
Biological Process	GO:0000237	leptotene	Spo11	IMP	MGI:MGI:2178805	Mouse	PMID:17010969
Biological Process	GO:0007141	male meiosis I	Spo11	IMP	MGI:MGI:3027823	Mouse	PMID:18694567
Biological Process	GO:0007141	male meiosis I	Spo11	IMP	MGI:MGI:2178805	Mouse	PMID:17696610
Biological Process	GO:0045141	meiotic telomere clustering	Spo11	IMP	MGI:MGI:2178805	Mouse	PMID:17010969
Biological Process	GO:0048477	oogenesis	Spo11	IMP	MGI:MGI:2178805	Mouse	PMID:22530760
Biological Process	GO:0001541	ovarian follicle development	Spo11	IMP	MGI:MGI:2178805	Mouse	PMID:15640358
Biological Process	GO:0034502	protein localization to chromosome	Spo11	IMP	MGI:MGI:2178805	Mouse	PMID:20551173
Biological Process	GO:0007131	reciprocal meiotic recombination	Spo11	IMP	MGI:MGI:2178805	Mouse	PMID:16307920
Biological Process	GO:0007286	spermatid development	Spo11	IMP	MGI:MGI:2178805	Mouse	PMID:17696610
Biological Process	GO:0007130	synaptonemal complex assembly	Spo11	IGI	MGI:MGI:3652039	Mouse	PMID:24589552
Biological Process	GO:0007130	synaptonemal complex assembly	Spo11	IMP	MGI:MGI:2178805	Mouse	PMID:27760146
Biological Process	GO:0007130	synaptonemal complex assembly	Spo11	IGI	MGI:MGI:1929645	Mouse	PMID:24589552

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern