Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPAG16
  • Mouse genes Spag16
  • Rat genes Spag16
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Spag16

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Spag16	IPI	UniProtKB:Q69ZM6	Mouse	MGI:MGI:3844768|PMID:19305393
Molecular Function	GO:0005515	protein binding	Spag16	IPI	PR:Q9JLI7	Mouse	PMID:12391165
Molecular Function	GO:0019901	protein kinase binding	Spag16	IPI	UniProtKB:O54863	Mouse	MGI:MGI:3814644|PMID:18367677
Cellular Component	GO:1990716	axonemal central apparatus	Spag16	IDA		Mouse	PMID:12391165
Cellular Component	GO:0005930	axoneme	Spag16	IDA		Mouse	MGI:MGI:3844768|PMID:19305393
Cellular Component	GO:0036126	sperm flagellum	Spag16	IDA		Mouse	MGI:MGI:6201947|PMID:27682589
Biological Process	GO:0035082	axoneme assembly	SPAG16	IMP		Human	PMID:17699735
Biological Process	GO:0090660	cerebrospinal fluid circulation	Spag16	IGI	MGI:MGI:1354388	Mouse	PMID:17323374
Biological Process	GO:0060271	cilium assembly	Spag16	IDA		Mouse	MGI:MGI:3844768|PMID:19305393
Biological Process	GO:0120197	mucociliary clearance	Spag16	IGI	MGI:MGI:1354388	Mouse	PMID:17323374
Biological Process	GO:0007288	sperm axoneme assembly	Spag16	IMP	MGI:MGI:3606977	Mouse	PMID:15328412

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern