Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SOX12
  • Mouse genes Sox12
  • Rat genes Sox12
  • Zfish genes sox12
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sox12

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Sox12	IDA		Mouse	MGI:MGI:6203502|PMID:30190287
Molecular Function	GO:0003677	DNA binding	Sox12	IDA		Mouse	MGI:MGI:5009531|PMID:18403418
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Sox12	IDA		Mouse	MGI:MGI:3803393|PMID:18505825
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	SOX12	IDA		Human	PMID:28473536
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Sox12	IDA		Mouse	MGI:MGI:3803393|PMID:18505825
Cellular Component	GO:0005654	nucleoplasm	SOX12	IDA		Human	GO_REF:0000052
Cellular Component	GO:0032993	protein-DNA complex	Sox12	IDA		Mouse	MGI:MGI:3803393|PMID:18505825
Biological Process	GO:0045591	positive regulation of regulatory T cell differentiation	Sox12	IMP		Mouse	MGI:MGI:6203502|PMID:30190287
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Sox12	IDA		Mouse	MGI:MGI:5009531|PMID:18403418
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Sox12	IDA		Mouse	MGI:MGI:6203502|PMID:30190287
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Sox12	IDA		Mouse	MGI:MGI:3803393|PMID:18505825
Biological Process	GO:0021510	spinal cord development	Sox12	IDA		Mouse	MGI:MGI:3803393|PMID:18505825

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern