Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SMR3B
  • Mouse genes Smr2
  • Rat genes Smr3b,Vcsa2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Smr2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004866	endopeptidase inhibitor activity	Smr3b	IDA		Rat	PMID:12835417|RGD:8553855
Molecular Function	GO:0030414	peptidase inhibitor activity	Smr3b	IDA		Rat	PMID:12835417|RGD:8553855
Molecular Function	GO:0005515	protein binding	SMR3B	IPI	UniProtKB:Q9UMX0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SMR3B	IPI	UniProtKB:Q9UMX0-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SMR3B	IPI	UniProtKB:Q9NSC5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMR3B	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Cellular Component	GO:0070062	extracellular exosome	SMR3B	HDA		Human	PMID:23533145
Cellular Component	GO:0005576	extracellular region	Smr3b	IDA		Rat	PMID:8112327|RGD:8553437
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Smr3b	IDA		Rat	PMID:9321881|RGD:8553737
Biological Process	GO:0010466	negative regulation of peptidase activity	Smr3b	IDA		Rat	PMID:12835417|RGD:8553855
Biological Process	GO:0051930	regulation of sensory perception of pain	Smr3b	IDA		Rat	PMID:12835417|RGD:8553855

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern