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Gene Ontology Browser
Term Detail
GO term:negative regulation of peptidase activity
GO id:GO:0010466
Definition:Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins.
Number of paths to term: 13

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of catalytic activity
                                                is-anegative regulation of catalytic activity
                                                        is-anegative regulation of hydrolase activity
                                                                is-anegative regulation of ATPase activity +
                                                                is-anegative regulation of cyclic-nucleotide phosphodiesterase activity
                                                                is-anegative regulation of DNA N-glycosylase activity
                                                                is-anegative regulation of endo-1,4-beta-xylanase activity
                                                                is-anegative regulation of GTP cyclohydrolase I activity
                                                                is-anegative regulation of GTPase activity +
                                                                is-anegative regulation of helicase activity +
                                                                is-anegative regulation of histone deacetylase activity
                                                                is-anegative regulation of lipase activity +
                                                                is-anegative regulation of microtubule motor activity +
                                                                is-anegative regulation of nuclease activity +
                                                                is-anegative regulation of peptidase activity [GO:0010466] (233 genes, 324 annotations)
                                                                        is-anegative regulation of deubiquitinase activity
                                                                        is-anegative regulation of endopeptidase activity +
                                                                        is-anegative regulation of peptidase activity in other organism +
                                                                        is-anegative regulation of serine-type peptidase activity +
                                                                is-anegative regulation of phosphatase activity +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of catalytic activity
                                                is-aregulation of hydrolase activity
                                                        is-anegative regulation of hydrolase activity
                                                                is-anegative regulation of ATPase activity +
                                                                is-anegative regulation of cyclic-nucleotide phosphodiesterase activity
                                                                is-anegative regulation of DNA N-glycosylase activity
                                                                is-anegative regulation of endo-1,4-beta-xylanase activity
                                                                is-anegative regulation of GTP cyclohydrolase I activity
                                                                is-anegative regulation of GTPase activity +
                                                                is-anegative regulation of helicase activity +
                                                                is-anegative regulation of histone deacetylase activity
                                                                is-anegative regulation of lipase activity +
                                                                is-anegative regulation of microtubule motor activity +
                                                                is-anegative regulation of nuclease activity +
                                                                is-anegative regulation of peptidase activity [GO:0010466] (233 genes, 324 annotations)
                                                                        is-anegative regulation of deubiquitinase activity
                                                                        is-anegative regulation of endopeptidase activity +
                                                                        is-anegative regulation of peptidase activity in other organism +
                                                                        is-anegative regulation of serine-type peptidase activity +
                                                                is-anegative regulation of phosphatase activity +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of catalytic activity
                                                is-aregulation of hydrolase activity
                                                        is-aregulation of peptidase activity
                                                                is-anegative regulation of peptidase activity [GO:0010466] (233 genes, 324 annotations)
                                                                        is-anegative regulation of deubiquitinase activity
                                                                        is-anegative regulation of endopeptidase activity +
                                                                        is-anegative regulation of peptidase activity in other organism +
                                                                        is-anegative regulation of serine-type peptidase activity +
                                                                is-apositive regulation of peptidase activity +
                                                                is-aregulation of deubiquitinase activity +
                                                                is-aregulation of endopeptidase activity +
                                                                is-aregulation of serine-type peptidase activity +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of molecular function
                                is-anegative regulation of molecular function
                                        is-anegative regulation of catalytic activity
                                                is-anegative regulation of hydrolase activity
                                                        is-anegative regulation of ATPase activity +
                                                        is-anegative regulation of cyclic-nucleotide phosphodiesterase activity
                                                        is-anegative regulation of DNA N-glycosylase activity
                                                        is-anegative regulation of endo-1,4-beta-xylanase activity
                                                        is-anegative regulation of GTP cyclohydrolase I activity
                                                        is-anegative regulation of GTPase activity +
                                                        is-anegative regulation of helicase activity +
                                                        is-anegative regulation of histone deacetylase activity
                                                        is-anegative regulation of lipase activity +
                                                        is-anegative regulation of microtubule motor activity +
                                                        is-anegative regulation of nuclease activity +
                                                        is-anegative regulation of peptidase activity [GO:0010466] (233 genes, 324 annotations)
                                                                is-anegative regulation of deubiquitinase activity
                                                                is-anegative regulation of endopeptidase activity +
                                                                is-anegative regulation of peptidase activity in other organism +
                                                                is-anegative regulation of serine-type peptidase activity +
                                                        is-anegative regulation of phosphatase activity +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of molecular function
                                is-aregulation of catalytic activity
                                        is-anegative regulation of catalytic activity
                                                is-anegative regulation of hydrolase activity
                                                        is-anegative regulation of ATPase activity +
                                                        is-anegative regulation of cyclic-nucleotide phosphodiesterase activity
                                                        is-anegative regulation of DNA N-glycosylase activity
                                                        is-anegative regulation of endo-1,4-beta-xylanase activity
                                                        is-anegative regulation of GTP cyclohydrolase I activity
                                                        is-anegative regulation of GTPase activity +
                                                        is-anegative regulation of helicase activity +
                                                        is-anegative regulation of histone deacetylase activity
                                                        is-anegative regulation of lipase activity +
                                                        is-anegative regulation of microtubule motor activity +
                                                        is-anegative regulation of nuclease activity +
                                                        is-anegative regulation of peptidase activity [GO:0010466] (233 genes, 324 annotations)
                                                                is-anegative regulation of deubiquitinase activity
                                                                is-anegative regulation of endopeptidase activity +
                                                                is-anegative regulation of peptidase activity in other organism +
                                                                is-anegative regulation of serine-type peptidase activity +
                                                        is-anegative regulation of phosphatase activity +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of molecular function
                                is-aregulation of catalytic activity
                                        is-aregulation of hydrolase activity
                                                is-anegative regulation of hydrolase activity
                                                        is-anegative regulation of ATPase activity +
                                                        is-anegative regulation of cyclic-nucleotide phosphodiesterase activity
                                                        is-anegative regulation of DNA N-glycosylase activity
                                                        is-anegative regulation of endo-1,4-beta-xylanase activity
                                                        is-anegative regulation of GTP cyclohydrolase I activity
                                                        is-anegative regulation of GTPase activity +
                                                        is-anegative regulation of helicase activity +
                                                        is-anegative regulation of histone deacetylase activity
                                                        is-anegative regulation of lipase activity +
                                                        is-anegative regulation of microtubule motor activity +
                                                        is-anegative regulation of nuclease activity +
                                                        is-anegative regulation of peptidase activity [GO:0010466] (233 genes, 324 annotations)
                                                                is-anegative regulation of deubiquitinase activity
                                                                is-anegative regulation of endopeptidase activity +
                                                                is-anegative regulation of peptidase activity in other organism +
                                                                is-anegative regulation of serine-type peptidase activity +
                                                        is-anegative regulation of phosphatase activity +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of molecular function
                                is-aregulation of catalytic activity
                                        is-aregulation of hydrolase activity
                                                is-aregulation of peptidase activity
                                                        is-anegative regulation of peptidase activity [GO:0010466] (233 genes, 324 annotations)
                                                                is-anegative regulation of deubiquitinase activity
                                                                is-anegative regulation of endopeptidase activity +
                                                                is-anegative regulation of peptidase activity in other organism +
                                                                is-anegative regulation of serine-type peptidase activity +
                                                        is-apositive regulation of peptidase activity +
                                                        is-aregulation of deubiquitinase activity +
                                                        is-aregulation of endopeptidase activity +
                                                        is-aregulation of serine-type peptidase activity +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        regulatesregulation of metabolic process
                                is-aregulation of catalytic activity
                                        is-anegative regulation of catalytic activity
                                                is-anegative regulation of hydrolase activity
                                                        is-anegative regulation of ATPase activity +
                                                        is-anegative regulation of cyclic-nucleotide phosphodiesterase activity
                                                        is-anegative regulation of DNA N-glycosylase activity
                                                        is-anegative regulation of endo-1,4-beta-xylanase activity
                                                        is-anegative regulation of GTP cyclohydrolase I activity
                                                        is-anegative regulation of GTPase activity +
                                                        is-anegative regulation of helicase activity +
                                                        is-anegative regulation of histone deacetylase activity
                                                        is-anegative regulation of lipase activity +
                                                        is-anegative regulation of microtubule motor activity +
                                                        is-anegative regulation of nuclease activity +
                                                        is-anegative regulation of peptidase activity [GO:0010466] (233 genes, 324 annotations)
                                                                is-anegative regulation of deubiquitinase activity
                                                                is-anegative regulation of endopeptidase activity +
                                                                is-anegative regulation of peptidase activity in other organism +
                                                                is-anegative regulation of serine-type peptidase activity +
                                                        is-anegative regulation of phosphatase activity +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        regulatesregulation of metabolic process
                                is-aregulation of catalytic activity
                                        is-aregulation of hydrolase activity
                                                is-anegative regulation of hydrolase activity
                                                        is-anegative regulation of ATPase activity +
                                                        is-anegative regulation of cyclic-nucleotide phosphodiesterase activity
                                                        is-anegative regulation of DNA N-glycosylase activity
                                                        is-anegative regulation of endo-1,4-beta-xylanase activity
                                                        is-anegative regulation of GTP cyclohydrolase I activity
                                                        is-anegative regulation of GTPase activity +
                                                        is-anegative regulation of helicase activity +
                                                        is-anegative regulation of histone deacetylase activity
                                                        is-anegative regulation of lipase activity +
                                                        is-anegative regulation of microtubule motor activity +
                                                        is-anegative regulation of nuclease activity +
                                                        is-anegative regulation of peptidase activity [GO:0010466] (233 genes, 324 annotations)
                                                                is-anegative regulation of deubiquitinase activity
                                                                is-anegative regulation of endopeptidase activity +
                                                                is-anegative regulation of peptidase activity in other organism +
                                                                is-anegative regulation of serine-type peptidase activity +
                                                        is-anegative regulation of phosphatase activity +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        regulatesregulation of metabolic process
                                is-aregulation of catalytic activity
                                        is-aregulation of hydrolase activity
                                                is-aregulation of peptidase activity
                                                        is-anegative regulation of peptidase activity [GO:0010466] (233 genes, 324 annotations)
                                                                is-anegative regulation of deubiquitinase activity
                                                                is-anegative regulation of endopeptidase activity +
                                                                is-anegative regulation of peptidase activity in other organism +
                                                                is-anegative regulation of serine-type peptidase activity +
                                                        is-apositive regulation of peptidase activity +
                                                        is-aregulation of deubiquitinase activity +
                                                        is-aregulation of endopeptidase activity +
                                                        is-aregulation of serine-type peptidase activity +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of metabolic process
                                is-aregulation of catalytic activity
                                        is-anegative regulation of catalytic activity
                                                is-anegative regulation of hydrolase activity
                                                        is-anegative regulation of ATPase activity +
                                                        is-anegative regulation of cyclic-nucleotide phosphodiesterase activity
                                                        is-anegative regulation of DNA N-glycosylase activity
                                                        is-anegative regulation of endo-1,4-beta-xylanase activity
                                                        is-anegative regulation of GTP cyclohydrolase I activity
                                                        is-anegative regulation of GTPase activity +
                                                        is-anegative regulation of helicase activity +
                                                        is-anegative regulation of histone deacetylase activity
                                                        is-anegative regulation of lipase activity +
                                                        is-anegative regulation of microtubule motor activity +
                                                        is-anegative regulation of nuclease activity +
                                                        is-anegative regulation of peptidase activity [GO:0010466] (233 genes, 324 annotations)
                                                                is-anegative regulation of deubiquitinase activity
                                                                is-anegative regulation of endopeptidase activity +
                                                                is-anegative regulation of peptidase activity in other organism +
                                                                is-anegative regulation of serine-type peptidase activity +
                                                        is-anegative regulation of phosphatase activity +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of metabolic process
                                is-aregulation of catalytic activity
                                        is-aregulation of hydrolase activity
                                                is-anegative regulation of hydrolase activity
                                                        is-anegative regulation of ATPase activity +
                                                        is-anegative regulation of cyclic-nucleotide phosphodiesterase activity
                                                        is-anegative regulation of DNA N-glycosylase activity
                                                        is-anegative regulation of endo-1,4-beta-xylanase activity
                                                        is-anegative regulation of GTP cyclohydrolase I activity
                                                        is-anegative regulation of GTPase activity +
                                                        is-anegative regulation of helicase activity +
                                                        is-anegative regulation of histone deacetylase activity
                                                        is-anegative regulation of lipase activity +
                                                        is-anegative regulation of microtubule motor activity +
                                                        is-anegative regulation of nuclease activity +
                                                        is-anegative regulation of peptidase activity [GO:0010466] (233 genes, 324 annotations)
                                                                is-anegative regulation of deubiquitinase activity
                                                                is-anegative regulation of endopeptidase activity +
                                                                is-anegative regulation of peptidase activity in other organism +
                                                                is-anegative regulation of serine-type peptidase activity +
                                                        is-anegative regulation of phosphatase activity +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of metabolic process
                                is-aregulation of catalytic activity
                                        is-aregulation of hydrolase activity
                                                is-aregulation of peptidase activity
                                                        is-anegative regulation of peptidase activity [GO:0010466] (233 genes, 324 annotations)
                                                                is-anegative regulation of deubiquitinase activity
                                                                is-anegative regulation of endopeptidase activity +
                                                                is-anegative regulation of peptidase activity in other organism +
                                                                is-anegative regulation of serine-type peptidase activity +
                                                        is-apositive regulation of peptidase activity +
                                                        is-aregulation of deubiquitinase activity +
                                                        is-aregulation of endopeptidase activity +
                                                        is-aregulation of serine-type peptidase activity +


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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory