Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC7A6
  • Mouse genes Slc7a6
  • Rat genes Slc7a6
  • Zfish genes slc7a6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc7a6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0034618	arginine binding	SLC7A6	IDA		Human	PMID:19562367
Molecular Function	GO:0015174	basic amino acid transmembrane transporter activity	SLC7A6	IMP		Human	PMID:17197568
Molecular Function	GO:0061459	L-arginine transmembrane transporter activity	SLC7A6	IDA		Human	PMID:11311135
Molecular Function	GO:0061459	L-arginine transmembrane transporter activity	SLC7A6	IDA		Human	PMID:15756301
Molecular Function	GO:0106439	L-lysine:L-arginine antiporter activity	SLC7A6	IDA		Human	PMID:10903140
Molecular Function	GO:0005515	protein binding	SLC7A6	IPI	UniProtKB:Q9UPQ8	Human	PMID:32296183
Biological Process	GO:0031460	glycine betaine transport	Slc7a6	IDA		Mouse	MGI:MGI:6709018|PMID:24599290
Biological Process	GO:1903826	L-arginine transmembrane transport	SLC7A6	IDA		Human	PMID:10903140
Biological Process	GO:1903826	L-arginine transmembrane transport	SLC7A6	IDA		Human	PMID:11311135
Biological Process	GO:1903826	L-arginine transmembrane transport	SLC7A6	IDA		Human	PMID:15756301
Biological Process	GO:1903826	L-arginine transmembrane transport	SLC7A6	IDA		Human	PMID:16785209
Biological Process	GO:1903826	L-arginine transmembrane transport	SLC7A6	IMP		Human	PMID:31705628
Biological Process	GO:1903826	L-arginine transmembrane transport	Slc7a6	IMP		Rat	PMID:22401943|RGD:155663518
Biological Process	GO:1903826	L-arginine transmembrane transport	Slc7a6	IMP		Rat	PMID:26448619|RGD:11531816
Biological Process	GO:0015820	leucine transport	SLC7A6	IDA		Human	PMID:16785209
Biological Process	GO:0015804	neutral amino acid transport	SLC7A6	IDA		Human	PMID:10903140
Biological Process	GO:0006809	nitric oxide biosynthetic process	Slc7a6	IMP		Rat	PMID:26448619|RGD:11531816
Biological Process	GO:0015822	ornithine transport	SLC7A6	IMP		Human	PMID:17197568

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern