Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC7A2
  • Mouse genes Slc7a2
  • Rat genes Slc7a2
  • Zfish genes slc7a2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc7a2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0061459	L-arginine transmembrane transporter activity	Slc7a2	IDA		Mouse	MGI:MGI:708000|PMID:9174363
Molecular Function	GO:0061459	L-arginine transmembrane transporter activity	Slc7a2	IMP	MGI:MGI:2150359	Mouse	PMID:12675924
Molecular Function	GO:0061459	L-arginine transmembrane transporter activity	Slc7a2	IMP	MGI:MGI:2150359	Mouse	PMID:11278602
Molecular Function	GO:0061459	L-arginine transmembrane transporter activity	Slc7a2	IDA		Rat	PMID:11329533|RGD:1642932
Molecular Function	GO:0061459	L-arginine transmembrane transporter activity	Slc7a2	IDA		Rat	PMID:16998217|RGD:1642934
Molecular Function	GO:0061459	L-arginine transmembrane transporter activity	Slc7a2	IDA		Rat	PMID:8626679|RGD:1642931
Cellular Component	GO:0030054	cell junction	SLC7A2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	Slc7a2	IDA		Mouse	PMID:8187816
Cellular Component	GO:0005886	plasma membrane	SLC7A2	IDA		Human	GO_REF:0000052
Biological Process	GO:0051649	establishment of localization in cell	Slc7a2	IMP	MGI:MGI:2150359	Mouse	PMID:11278602
Biological Process	GO:0051649	establishment of localization in cell	Slc7a2	IMP	MGI:MGI:2150359	Mouse	PMID:12675924
Biological Process	GO:1903826	L-arginine transmembrane transport	Slc7a2	IDA		Mouse	MGI:MGI:708000|PMID:9174363
Biological Process	GO:1903826	L-arginine transmembrane transport	Slc7a2	IMP	MGI:MGI:2150359	Mouse	PMID:11278602
Biological Process	GO:1903826	L-arginine transmembrane transport	Slc7a2	IMP	MGI:MGI:2150359	Mouse	PMID:12675924
Biological Process	GO:1903826	L-arginine transmembrane transport	Slc7a2	IDA		Rat	PMID:11329533|RGD:1642932
Biological Process	GO:1903826	L-arginine transmembrane transport	Slc7a2	IDA		Rat	PMID:16998217|RGD:1642934
Biological Process	GO:1903826	L-arginine transmembrane transport	Slc7a2	IDA		Rat	PMID:8626679|RGD:1642931
Biological Process	GO:0042116	macrophage activation	Slc7a2	IMP	MGI:MGI:2150359	Mouse	PMID:16703566
Biological Process	GO:0006809	nitric oxide biosynthetic process	Slc7a2	IMP	MGI:MGI:2150359	Mouse	PMID:12675924
Biological Process	GO:0002537	nitric oxide production involved in inflammatory response	Slc7a2	IMP	MGI:MGI:2150359	Mouse	PMID:17003120
Biological Process	GO:0002537	nitric oxide production involved in inflammatory response	Slc7a2	IMP	MGI:MGI:2150359	Mouse	PMID:11278602
Biological Process	GO:0050727	regulation of inflammatory response	Slc7a2	IMP	MGI:MGI:2150359	Mouse	PMID:17003120
Biological Process	GO:0043030	regulation of macrophage activation	Slc7a2	IMP		Mouse	MGI:MGI:3774232|PMID:16670299

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern