Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC6A5
  • Mouse genes Slc6a5
  • Rat genes Slc6a5
  • Zfish genes slc6a5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc6a5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015187	glycine transmembrane transporter activity	Slc6a5	IDA		Rat	PMID:8226790|RGD:730010
Molecular Function	GO:0015375	glycine:sodium symporter activity	SLC6A5	IDA		Human	PMID:10381548
Molecular Function	GO:0015375	glycine:sodium symporter activity	SLC6A5	IMP		Human	PMID:10606742
Molecular Function	GO:0015375	glycine:sodium symporter activity	SLC6A5	IDA		Human	PMID:16751771
Molecular Function	GO:0015375	glycine:sodium symporter activity	SLC6A5	IMP		Human	PMID:31370103
Molecular Function	GO:0015375	glycine:sodium symporter activity	SLC6A5	IDA		Human	PMID:9845349
Molecular Function	GO:0015375	glycine:sodium symporter activity	Slc6a5	IDA		Rat	PMID:8226790|RGD:730010
Cellular Component	GO:0031045	dense core granule	Slc6a5	IDA		Rat	PMID:12091465|RGD:30309946
Cellular Component	GO:0005768	endosome	Slc6a5	IDA		Rat	PMID:12091465|RGD:30309946
Cellular Component	GO:0098690	glycinergic synapse	Slc6a5	IDA		Mouse	PMID:14622583
Cellular Component	GO:0098690	glycinergic synapse	Slc6a5	IMP		Mouse	PMID:14622583
Cellular Component	GO:0098690	glycinergic synapse	Slc6a5	EXP		Mouse	PMID:23486948
Cellular Component	GO:0098690	glycinergic synapse	Slc6a5	IDA		Mouse	PMID:23486948
Cellular Component	GO:0098690	glycinergic synapse	Slc6a5	IDA		Rat	PMID:19374720|RGD:13702296
Cellular Component	GO:0098690	glycinergic synapse	Slc6a5	IDA		Rat	PMID:7751957|RGD:13702203
Cellular Component	GO:0005886	plasma membrane	SLC6A5	IDA		Human	PMID:16751771
Cellular Component	GO:0005886	plasma membrane	SLC6A5	IMP		Human	PMID:31370103
Cellular Component	GO:0042734	presynaptic membrane	Slc6a5	IDA		Rat	PMID:19374720|RGD:13702296
Cellular Component	GO:0042734	presynaptic membrane	Slc6a5	IDA		Rat	PMID:7751957|RGD:13702203
Biological Process	GO:1903804	glycine import across plasma membrane	SLC6A5	IDA		Human	PMID:16751771
Biological Process	GO:0015816	glycine transport	Slc6a5	IDA		Rat	PMID:8226790|RGD:730010
Biological Process	GO:0098810	neurotransmitter reuptake	Slc6a5	EXP		Mouse	PMID:23486948
Biological Process	GO:0098810	neurotransmitter reuptake	Slc6a5	IDA		Mouse	PMID:23486948
Biological Process	GO:0001504	neurotransmitter uptake	Slc6a5	IDA		Mouse	PMID:14622583
Biological Process	GO:0001504	neurotransmitter uptake	Slc6a5	IMP		Mouse	PMID:14622583
Biological Process	GO:0060012	synaptic transmission, glycinergic	SLC6A5	IMP		Human	PMID:16751771

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern