Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC6A18
  • Mouse genes Slc6a18
  • Rat genes Slc6a18
  • Zfish genes slc6a18
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc6a18

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015175	neutral L-amino acid transmembrane transporter activity	Slc6a18	IMP		Mouse	MGI:MGI:6120366|PMID:26240152
Molecular Function	GO:0140931	neutral L-amino acid:sodium:chloride symporter activity	Slc6a18	IDA		Mouse	MGI:MGI:7408278|PMID:20377526
Molecular Function	GO:0140931	neutral L-amino acid:sodium:chloride symporter activity	Slc6a18	IDA		Mouse	MGI:MGI:5913069|PMID:19478081
Molecular Function	GO:0140931	neutral L-amino acid:sodium:chloride symporter activity	Slc6a18	IDA		Mouse	MGI:MGI:6120366|PMID:26240152
Molecular Function	GO:0005515	protein binding	Slc6a18	IPI	PR:Q9ESG4	Mouse	PMID:17167413
Cellular Component	GO:0016324	apical plasma membrane	Slc6a18	IDA		Mouse	MGI:MGI:5913069|PMID:19478081
Cellular Component	GO:0016324	apical plasma membrane	Slc6a18	IDA		Mouse	MGI:MGI:7408278|PMID:20377526
Cellular Component	GO:0031526	brush border membrane	Slc6a18	IDA		Mouse	PMID:17167413
Cellular Component	GO:0005886	plasma membrane	Slc6a18	IDA		Mouse	MGI:MGI:6120366|PMID:26240152
Cellular Component	GO:0005886	plasma membrane	Slc6a18	IDA		Mouse	PMID:9932288
Biological Process	GO:0003333	amino acid transmembrane transport	Slc6a18	IDA		Mouse	PMID:17167413
Biological Process	GO:0006972	hyperosmotic response	Slc6a18	IEP		Rat	PMID:15056985|RGD:1580633
Biological Process	GO:0015804	neutral amino acid transport	Slc6a18	IDA		Mouse	MGI:MGI:7408278|PMID:20377526
Biological Process	GO:0015804	neutral amino acid transport	Slc6a18	IDA		Mouse	MGI:MGI:5913069|PMID:19478081
Biological Process	GO:1990297	renal amino acid absorption	Slc6a18	IMP		Mouse	MGI:MGI:5913069|PMID:19478081
Biological Process	GO:0006970	response to osmotic stress	Slc6a18	IEP		Rat	PMID:7943364|RGD:68841

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern