Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC6A12
  • Mouse genes Slc6a12
  • Rat genes Slc6a12
  • Zfish genes si:ch211-132b12.1,si:ch211-132b12.2,si:ch211-132b12.3,si:ch211-132b12.6,slc6a11a,slc6a22.1,slc6a22.2,zgc:158427
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc6a12

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005332	gamma-aminobutyric acid:sodium:chloride symporter activity	SLC6A12	IDA		Human	PMID:7589472
Molecular Function	GO:0005332	gamma-aminobutyric acid:sodium:chloride symporter activity	SLC6A12	IDA		Human	PMID:7861179
Molecular Function	GO:0005332	gamma-aminobutyric acid:sodium:chloride symporter activity	Slc6a12	IDA		Mouse	MGI:MGI:50760|PMID:1517200
Molecular Function	GO:0008028	monocarboxylic acid transmembrane transporter activity	SLC6A12	IDA		Human	PMID:29175673
Molecular Function	GO:0005515	protein binding	SLC6A12	IPI	UniProtKB:Q14160	Human	PMID:21525870
Molecular Function	GO:0005515	protein binding	SLC6A12	IPI	UniProtKB:Q14160	Human	PMID:24550280
Molecular Function	GO:0005515	protein binding	SLC6A12	IPI	UniProtKB:Q04864	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SLC6A12	IPI	UniProtKB:P11912	Human	PMID:32296183
Cellular Component	GO:0016020	membrane	Slc6a12	IDA		Rat	PMID:15073174|RGD:1303365
Biological Process	GO:0071474	cellular hyperosmotic response	Slc6a12	IEP		Rat	PMID:17022965|RGD:2316970
Biological Process	GO:0015812	gamma-aminobutyric acid transport	SLC6A12	IDA		Human	PMID:7589472
Biological Process	GO:0015812	gamma-aminobutyric acid transport	SLC6A12	IDA		Human	PMID:7861179
Biological Process	GO:0015812	gamma-aminobutyric acid transport	Slc6a12	IDA		Mouse	MGI:MGI:50760|PMID:1517200
Biological Process	GO:0031460	glycine betaine transport	Slc6a12	IDA		Mouse	MGI:MGI:50760|PMID:1517200
Biological Process	GO:0009992	intracellular water homeostasis	Slc6a12	IDA		Rat	PMID:20394832|RGD:2324693
Biological Process	GO:0015718	monocarboxylic acid transport	SLC6A12	IDA		Human	PMID:29175673
Biological Process	GO:0010033	response to organic substance	Slc6a12	IEP		Rat	PMID:15248296|RGD:1643206

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern