Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Slc5a5

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes SLC5A5
- Mouse genes Slc5a5
- Rat genes Slc5a5
- Zfish genes slc5a5
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc5a5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015111	iodide transmembrane transporter activity	SLC5A5	IMP		Human	PMID:12021185
Molecular Function	GO:0015111	iodide transmembrane transporter activity	SLC5A5	IDA		Human	PMID:21988488
Molecular Function	GO:0015111	iodide transmembrane transporter activity	SLC5A5	IDA		Human	PMID:26599396
Molecular Function	GO:0015111	iodide transmembrane transporter activity	SLC5A5	IMP		Human	PMID:26831514
Molecular Function	GO:0015111	iodide transmembrane transporter activity	Slc5a5	IMP		Rat	PMID:18339708\|RGD:15090852
Molecular Function	GO:0015373	monoatomic anion:sodium symporter activity	SLC5A5	IDA		Human	PMID:12488351
Molecular Function	GO:0005515	protein binding	SLC5A5	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC5A5	IPI	UniProtKB:P0DPK4	Human	PMID:32296183
Molecular Function	GO:0042803	protein homodimerization activity	SLC5A5	IDA		Human	PMID:18372236
Molecular Function	GO:0042803	protein homodimerization activity	SLC5A5	IDA		Human	PMID:20797386
Molecular Function	GO:0042803	protein homodimerization activity	SLC5A5	IDA		Human	PMID:31310151
Molecular Function	GO:0008507	sodium:iodide symporter activity	SLC5A5	IDA		Human	PMID:12488351
Molecular Function	GO:0008507	sodium:iodide symporter activity	SLC5A5	IDA		Human	PMID:18372236
Molecular Function	GO:0008507	sodium:iodide symporter activity	SLC5A5	IMP		Human	PMID:18708479
Molecular Function	GO:0008507	sodium:iodide symporter activity	SLC5A5	IDA		Human	PMID:20797386
Molecular Function	GO:0008507	sodium:iodide symporter activity	SLC5A5	IMP		Human	PMID:31310151
Molecular Function	GO:0008507	sodium:iodide symporter activity	SLC5A5	IDA		Human	PMID:32084174
Molecular Function	GO:0008507	sodium:iodide symporter activity	SLC5A5	IDA		Human	PMID:8806637
Molecular Function	GO:0008507	sodium:iodide symporter activity	SLC5A5	IDA		Human	PMID:9329364
Molecular Function	GO:0008507	sodium:iodide symporter activity	Slc5a5	IDA		Mouse	MGI:MGI:7310192\|PMID:18372236
Molecular Function	GO:0008507	sodium:iodide symporter activity	Slc5a5	IDA		Mouse	MGI:MGI:7310372\|PMID:11716040
Molecular Function	GO:0008507	sodium:iodide symporter activity	Slc5a5	IDA		Mouse	MGI:MGI:7310193\|PMID:32084174
Molecular Function	GO:0008507	sodium:iodide symporter activity	Slc5a5	IDA		Mouse	PMID:11431151
Molecular Function	GO:0008507	sodium:iodide symporter activity	Slc5a5	IDA		Rat	PMID:32084174\|RGD:152995564
Molecular Function	GO:0008507	sodium:iodide symporter activity	Slc5a5	IDA		Rat	PMID:8559252\|RGD:68854
Molecular Function	GO:0008507	sodium:iodide symporter activity	Slc5a5	IDA		Rat	PMID:9341168\|RGD:152995539
Molecular Function	GO:0008507	sodium:iodide symporter activity	slc5a5	IDA		Zfish	PMID:32084174
Molecular Function	GO:0015293	symporter activity	Slc5a5	IDA		Mouse	PMID:11431151
Cellular Component	GO:0005737	cytoplasm	SLC5A5	IDA		Human	PMID:18372236
Cellular Component	GO:0005737	cytoplasm	Slc5a5	IDA		Mouse	MGI:MGI:7310192\|PMID:18372236
Cellular Component	GO:0070062	extracellular exosome	SLC5A5	HDA		Human	PMID:19199708
Cellular Component	GO:1903561	extracellular vesicle	SLC5A5	HDA		Human	PMID:24769233
Cellular Component	GO:0005634	nucleus	SLC5A5	IDA		Human	PMID:15961562
Cellular Component	GO:0005886	plasma membrane	SLC5A5	IDA		Human	PMID:26599396
Cellular Component	GO:0005886	plasma membrane	SLC5A5	IDA		Human	PMID:18372236
Cellular Component	GO:0005886	plasma membrane	SLC5A5	IMP		Human	PMID:18708479
Cellular Component	GO:0005886	plasma membrane	SLC5A5	IDA		Human	PMID:20797386
Cellular Component	GO:0005886	plasma membrane	SLC5A5	IMP		Human	PMID:31310151
Cellular Component	GO:0005886	plasma membrane	Slc5a5	IDA		Mouse	MGI:MGI:7310192\|PMID:18372236
Cellular Component	GO:0005886	plasma membrane	Slc5a5	IDA		Rat	PMID:18339708\|RGD:15090852
Cellular Component	GO:0005886	plasma membrane	Slc5a5	IDA		Rat	PMID:12145342\|RGD:727400
Cellular Component	GO:0005886	plasma membrane	Slc5a5	IDA		Rat	PMID:9341168\|RGD:152995539
Biological Process	GO:0071320	cellular response to cAMP	SLC5A5	IEP		Human	PMID:12021185
Biological Process	GO:1904322	cellular response to forskolin	SLC5A5	IDA		Human	PMID:9329364
Biological Process	GO:0071371	cellular response to gonadotropin stimulus	SLC5A5	IEP		Human	PMID:12021185
Biological Process	GO:1904401	cellular response to Thyroid stimulating hormone	SLC5A5	IDA		Human	PMID:9329364
Biological Process	GO:1904200	iodide transmembrane transport	SLC5A5	IDA		Human	PMID:21988488
Biological Process	GO:1904200	iodide transmembrane transport	SLC5A5	IDA		Human	PMID:26599396
Biological Process	GO:1904200	iodide transmembrane transport	SLC5A5	IMP		Human	PMID:26831514
Biological Process	GO:1904200	iodide transmembrane transport	Slc5a5	IMP		Rat	PMID:18339708\|RGD:15090852
Biological Process	GO:0015705	iodide transport	SLC5A5	IMP		Human	PMID:12021185
Biological Process	GO:0015705	iodide transport	Slc5a5	IDA		Rat	PMID:8559252\|RGD:68854
Biological Process	GO:0015705	iodide transport	slc5a5	IDA		Zfish	PMID:32084174\|ZFIN:ZDB-PUB-200225-22
Biological Process	GO:0098656	monoatomic anion transmembrane transport	slc5a5	IDA		Zfish	PMID:32084174\|ZFIN:ZDB-PUB-200225-22
Biological Process	GO:0035725	sodium ion transmembrane transport	slc5a5	IDA		Zfish	PMID:32084174\|ZFIN:ZDB-PUB-200225-22
Biological Process	GO:0006814	sodium ion transport	Slc5a5	IDA		Rat	PMID:8559252\|RGD:68854
Biological Process	GO:0055085	transmembrane transport	Slc5a5	IDA		Mouse	MGI:MGI:2137080\|PMID:11431151

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.