Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC5A2
  • Mouse genes Slc5a2
  • Rat genes Slc5a2
  • Zfish genes slc5a2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc5a2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015151	alpha-glucoside transmembrane transporter activity	SLC5A2	IDA		Human	PMID:20980548
Molecular Function	GO:0015151	alpha-glucoside transmembrane transporter activity	SLC5A2	IDA		Human	PMID:26376857
Molecular Function	GO:0055056	D-glucose transmembrane transporter activity	SLC5A2	IDA		Human	PMID:20980548
Molecular Function	GO:0005412	glucose:sodium symporter activity	SLC5A2	EXP		Human	PMID:11133510
Molecular Function	GO:0005412	glucose:sodium symporter activity	SLC5A2	IDA		Human	PMID:20980548
Molecular Function	GO:0005412	glucose:sodium symporter activity	SLC5A2	IDA		Human	PMID:28592437
Molecular Function	GO:0005412	glucose:sodium symporter activity	Slc5a2	IDA		Rat	PMID:14506074|RGD:1599050
Molecular Function	GO:0005412	glucose:sodium symporter activity	Slc5a2	IDA		Rat	PMID:7493971|RGD:633997
Molecular Function	GO:0005515	protein binding	SLC5A2	IPI	UniProtKB:Q13113	Human	PMID:34880493
Molecular Function	GO:0005515	protein binding	Slc5a2	IPI	UniProtKB:P22361	Mouse	MGI:MGI:3619106|PMID:11269503
Cellular Component	GO:0016324	apical plasma membrane	Slc5a2	IDA		Mouse	MGI:MGI:4943531|PMID:20616166
Cellular Component	GO:0031526	brush border membrane	Slc5a2	IDA		Rat	PMID:14506074|RGD:1599050
Cellular Component	GO:0070062	extracellular exosome	SLC5A2	HDA		Human	PMID:19056867
Cellular Component	GO:0016020	membrane	Slc5a2	IDA		Rat	PMID:7493971|RGD:633997
Cellular Component	GO:0005886	plasma membrane	SLC5A2	IDA		Human	PMID:26376857
Biological Process	GO:0000017	alpha-glucoside transport	SLC5A2	IDA		Human	PMID:20980548
Biological Process	GO:0000017	alpha-glucoside transport	SLC5A2	IDA		Human	PMID:26376857
Biological Process	GO:0098708	glucose import across plasma membrane	SLC5A2	IDA		Human	PMID:20980548
Biological Process	GO:1904659	glucose transmembrane transport	Slc5a2	IDA		Rat	PMID:14506074|RGD:1599050
Biological Process	GO:1904659	glucose transmembrane transport	Slc5a2	IDA		Rat	PMID:7493971|RGD:633997
Biological Process	GO:0035811	negative regulation of urine volume	Slc5a2	IMP		Rat	PMID:29790389|RGD:13673897
Biological Process	GO:0035623	renal glucose absorption	Slc5a2	IMP		Mouse	MGI:MGI:4943531|PMID:20616166
Biological Process	GO:0036359	renal potassium excretion	Slc5a2	IMP		Rat	PMID:29790389|RGD:13673897
Biological Process	GO:0098719	sodium ion import across plasma membrane	SLC5A2	IDA		Human	PMID:20980548

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern