Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC4A3
  • Mouse genes Slc4a3
  • Rat genes Slc4a3
  • Zfish genes slc4a3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc4a3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015106	bicarbonate transmembrane transporter activity	SLC4A3	IMP		Human	PMID:29167417
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	Slc4a3	IDA		Mouse	MGI:MGI:64573|PMID:2686841
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	Slc4a3	IDA		Rat	PMID:10548554|RGD:155663554
Molecular Function	GO:0019899	enzyme binding	Slc4a3	IPI	RGD:1315034	Rat	PMID:17652430|RGD:9999376
Molecular Function	GO:0005515	protein binding	SLC4A3	IPI	UniProtKB:Q12933	Human	PMID:32296183
Cellular Component	GO:0009897	external side of plasma membrane	SLC4A3	IMP		Human	PMID:29167417
Cellular Component	GO:0005886	plasma membrane	Slc4a3	IDA		Mouse	PMID:2686841
Cellular Component	GO:0005886	plasma membrane	Slc4a3	IDA		Rat	PMID:10548554|RGD:155663554
Biological Process	GO:0015701	bicarbonate transport	SLC4A3	IMP		Human	PMID:29167417
Biological Process	GO:0061337	cardiac conduction	SLC4A3	IMP		Human	PMID:29167417
Biological Process	GO:0086001	cardiac muscle cell action potential	slc4a3	IMP	ZFIN:ZDB-MRPHLNO-180426-1	Zfish	PMID:29167417
Biological Process	GO:0051453	regulation of intracellular pH	Slc4a3	IDA		Mouse	PMID:2686841

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern