Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC43A2
  • Mouse genes Slc43a2
  • Rat genes Slc43a2
  • Zfish genes slc43a2a,slc43a2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc43a2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015179	L-amino acid transmembrane transporter activity	Slc43a2	IDA		Mouse	PMID:15659399
Molecular Function	GO:0015188	L-isoleucine transmembrane transporter activity	SLC43A2	IDA		Human	PMID:15659399
Molecular Function	GO:0015190	L-leucine transmembrane transporter activity	SLC43A2	IDA		Human	PMID:15659399
Molecular Function	GO:0015190	L-leucine transmembrane transporter activity	Slc43a2	IDA		Mouse	MGI:MGI:5812749|PMID:25480797
Molecular Function	GO:0015190	L-leucine transmembrane transporter activity	Slc43a2	IDA		Mouse	MGI:MGI:3576957|PMID:15659399
Molecular Function	GO:0015191	L-methionine transmembrane transporter activity	SLC43A2	IDA		Human	PMID:15659399
Molecular Function	GO:0015192	L-phenylalanine transmembrane transporter activity	SLC43A2	IDA		Human	PMID:30379325
Molecular Function	GO:0015192	L-phenylalanine transmembrane transporter activity	Slc43a2	IDA		Mouse	MGI:MGI:5812749|PMID:25480797
Molecular Function	GO:0005515	protein binding	SLC43A2	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC43A2	IPI	UniProtKB:P0DPK4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC43A2	IPI	UniProtKB:Q07627	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC43A2	IPI	UniProtKB:Q8IUG1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC43A2	IPI	UniProtKB:Q92764	Human	PMID:32296183
Cellular Component	GO:0016323	basolateral plasma membrane	Slc43a2	IDA		Mouse	MGI:MGI:5812749|PMID:25480797
Cellular Component	GO:0016323	basolateral plasma membrane	Slc43a2	IDA		Mouse	MGI:MGI:6390111|PMID:30379325
Cellular Component	GO:0005886	plasma membrane	Slc43a2	IDA		Mouse	PMID:15659399
Biological Process	GO:0015818	isoleucine transport	SLC43A2	IDA		Human	PMID:15659399
Biological Process	GO:1902475	L-alpha-amino acid transmembrane transport	Slc43a2	IDA		Mouse	MGI:MGI:3576957|PMID:15659399
Biological Process	GO:0015807	L-amino acid transport	Slc43a2	IDA		Mouse	PMID:15659399
Biological Process	GO:0015820	leucine transport	SLC43A2	IDA		Human	PMID:15659399
Biological Process	GO:0015820	leucine transport	Slc43a2	IDA		Mouse	MGI:MGI:5812749|PMID:25480797
Biological Process	GO:0015820	leucine transport	Slc43a2	IDA		Mouse	MGI:MGI:3576957|PMID:15659399
Biological Process	GO:0015821	methionine transport	SLC43A2	IDA		Human	PMID:15659399
Biological Process	GO:0051956	negative regulation of amino acid transport	SLC43A2	IDA		Human	PMID:26305885
Biological Process	GO:0060358	negative regulation of leucine import	SLC43A2	IDA		Human	PMID:26305885
Biological Process	GO:0015823	phenylalanine transport	SLC43A2	IDA		Human	PMID:30379325
Biological Process	GO:0015823	phenylalanine transport	Slc43a2	IDA		Mouse	MGI:MGI:5812749|PMID:25480797

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern