Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC43A1
  • Mouse genes Slc43a1
  • Rat genes Slc43a1
  • Zfish genes slc43a1a,slc43a1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc43a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015179	L-amino acid transmembrane transporter activity	Slc43a1	IDA		Mouse	PMID:15659399
Molecular Function	GO:0015188	L-isoleucine transmembrane transporter activity	SLC43A1	IDA		Human	PMID:12930836
Molecular Function	GO:0015188	L-isoleucine transmembrane transporter activity	Slc43a1	IDA		Mouse	MGI:MGI:3700080|PMID:17322374
Molecular Function	GO:0015190	L-leucine transmembrane transporter activity	SLC43A1	IDA		Human	PMID:12930836
Molecular Function	GO:0015190	L-leucine transmembrane transporter activity	Slc43a1	IDA		Mouse	MGI:MGI:3700080|PMID:17322374
Molecular Function	GO:0005304	L-valine transmembrane transporter activity	SLC43A1	IDA		Human	PMID:12930836
Molecular Function	GO:0005304	L-valine transmembrane transporter activity	Slc43a1	IDA		Mouse	MGI:MGI:3700080|PMID:17322374
Molecular Function	GO:0015175	neutral L-amino acid transmembrane transporter activity	SLC43A1	IDA		Human	PMID:12930836
Molecular Function	GO:0015175	neutral L-amino acid transmembrane transporter activity	Slc43a1	IDA		Mouse	MGI:MGI:3700080|PMID:17322374
Molecular Function	GO:0005515	protein binding	SLC43A1	IPI	UniProtKB:Q9BYV9	Human	PMID:32296183
Cellular Component	GO:0016324	apical plasma membrane	SLC43A1	IDA		Human	PMID:19443642
Cellular Component	GO:0005886	plasma membrane	Slc43a1	IDA		Mouse	MGI:MGI:3700080|PMID:17322374
Cellular Component	GO:0098846	podocyte foot	SLC43A1	IDA		Human	PMID:19443642
Biological Process	GO:0015818	isoleucine transport	SLC43A1	IDA		Human	PMID:12930836
Biological Process	GO:0015818	isoleucine transport	Slc43a1	IDA		Mouse	MGI:MGI:3700080|PMID:17322374
Biological Process	GO:1902475	L-alpha-amino acid transmembrane transport	Slc43a1	IDA		Mouse	MGI:MGI:3576957|PMID:15659399
Biological Process	GO:0015807	L-amino acid transport	Slc43a1	IDA		Mouse	PMID:15659399
Biological Process	GO:1903785	L-valine transmembrane transport	SLC43A1	IDA		Human	PMID:12930836
Biological Process	GO:1903785	L-valine transmembrane transport	Slc43a1	IDA		Mouse	MGI:MGI:3700080|PMID:17322374
Biological Process	GO:0015820	leucine transport	SLC43A1	IDA		Human	PMID:12930836
Biological Process	GO:0015820	leucine transport	Slc43a1	IDA		Mouse	MGI:MGI:3700080|PMID:17322374
Biological Process	GO:0051956	negative regulation of amino acid transport	SLC43A1	IDA		Human	PMID:26305885
Biological Process	GO:0060358	negative regulation of leucine import	SLC43A1	IDA		Human	PMID:26305885
Biological Process	GO:0015804	neutral amino acid transport	SLC43A1	IDA		Human	PMID:12930836
Biological Process	GO:0015804	neutral amino acid transport	Slc43a1	IDA		Mouse	MGI:MGI:3700080|PMID:17322374
Biological Process	GO:0072015	podocyte development	slc43a1a	IMP	ZFIN:ZDB-MRPHLNO-090924-5	Zfish	PMID:19443642
Biological Process	GO:0072015	podocyte development	slc43a1a	IMP	ZFIN:ZDB-MRPHLNO-090924-4	Zfish	PMID:19443642

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern