Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC30A1
  • Mouse genes Slc30a1
  • Rat genes Slc30a1
  • Zfish genes slc30a1a,slc30a1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc30a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019855	calcium channel inhibitor activity	Slc30a1	IDA		Mouse	MGI:MGI:4456947|PMID:15451416
Molecular Function	GO:0019855	calcium channel inhibitor activity	Slc30a1	IMP		Rat	PMID:16741752|RGD:8554228
Molecular Function	GO:0005515	protein binding	SLC30A1	IPI	UniProtKB:P06927	Human	PMID:18158319
Molecular Function	GO:0005515	protein binding	SLC30A1	IPI	UniProtKB:Q7Z403	Human	PMID:18158319
Molecular Function	GO:0005515	protein binding	SLC30A1	IPI	UniProtKB:Q8IU68	Human	PMID:18158319
Molecular Function	GO:0005515	protein binding	SLC30A1	IPI	UniProtKB:Q9BRI3	Human	PMID:25657003
Molecular Function	GO:0005385	zinc ion transmembrane transporter activity	Slc30a1	IDA		Rat	PMID:7882967|RGD:61756
Molecular Function	GO:0005385	zinc ion transmembrane transporter activity	Slc30a1	IMP		Rat	PMID:7882967|RGD:61756
Molecular Function	GO:0140826	zinc:proton antiporter activity	Slc30a1	IDA		Rat	PMID:24951051|RGD:155230788
Cellular Component	GO:0016323	basolateral plasma membrane	SLC30A1	IDA		Human	PMID:31471319
Cellular Component	GO:0005737	cytoplasm	SLC30A1	IDA		Human	PMID:18158319
Cellular Component	GO:0030659	cytoplasmic vesicle membrane	SLC30A1	IDA		Human	PMID:32441444
Cellular Component	GO:0005783	endoplasmic reticulum	SLC30A1	IDA		Human	PMID:18158319
Cellular Component	GO:0005794	Golgi apparatus	SLC30A1	IDA		Human	PMID:18158319
Cellular Component	GO:0016020	membrane	Slc30a1	IDA		Rat	PMID:7882967|RGD:61756
Cellular Component	GO:0031965	nuclear membrane	SLC30A1	IDA		Human	PMID:18158319
Cellular Component	GO:0005886	plasma membrane	SLC30A1	IDA		Human	PMID:17349999
Cellular Component	GO:0005886	plasma membrane	SLC30A1	IDA		Human	PMID:32441444
Cellular Component	GO:0005886	plasma membrane	Slc30a1	IDA		Rat	PMID:24951051|RGD:155230788
Cellular Component	GO:0005886	plasma membrane	Slc30a1	IDA		Rat	PMID:7882967|RGD:61756
Cellular Component	GO:0098839	postsynaptic density membrane	Slc30a1	IDA		Rat	PMID:24602382|RGD:13702407
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Slc30a1	IDA		Rat	PMID:24602382|RGD:13702407
Cellular Component	GO:0030315	T-tubule	Slc30a1	IDA		Rat	PMID:16741752|RGD:8554228
Biological Process	GO:0070574	cadmium ion transmembrane transport	Slc30a1	IMP		Rat	PMID:16741752|RGD:8554228
Biological Process	GO:0070509	calcium ion import	Slc30a1	IMP		Rat	PMID:16741752|RGD:8554228
Biological Process	GO:0042742	defense response to bacterium	SLC30A1	IDA		Human	PMID:32441444
Biological Process	GO:0071585	detoxification of cadmium ion	Slc30a1	IMP		Rat	PMID:16741752|RGD:8554228
Biological Process	GO:0001701	in utero embryonic development	Slc30a1	IMP	MGI:MGI:3056498	Mouse	PMID:15452870
Biological Process	GO:0006874	intracellular calcium ion homeostasis	Slc30a1	IDA		Mouse	MGI:MGI:4456947|PMID:15451416
Biological Process	GO:0006882	intracellular zinc ion homeostasis	Slc30a1	IDA		Mouse	MGI:MGI:4456947|PMID:15451416
Biological Process	GO:0006882	intracellular zinc ion homeostasis	Slc30a1	IMP	MGI:MGI:3056498	Mouse	PMID:15452870
Biological Process	GO:0090281	negative regulation of calcium ion import	Slc30a1	IDA		Mouse	MGI:MGI:4456947|PMID:15451416
Biological Process	GO:0046929	negative regulation of neurotransmitter secretion	Slc30a1	IMP		Rat	PMID:16741752|RGD:8554228
Biological Process	GO:0071584	negative regulation of zinc ion transmembrane import	Slc30a1	IDA		Mouse	MGI:MGI:4456947|PMID:15451416
Biological Process	GO:0010043	response to zinc ion	slc30a1a	IDA		Zfish	PMID:18477665
Biological Process	GO:0140882	zinc export across plasma membrane	Slc30a1	IMP		Rat	PMID:19095042|RGD:155230749
Biological Process	GO:0140882	zinc export across plasma membrane	Slc30a1	IDA		Rat	PMID:24951051|RGD:155230788
Biological Process	GO:0062111	zinc ion import into organelle	SLC30A1	IDA		Human	PMID:32441444
Biological Process	GO:0006829	zinc ion transport	Slc30a1	IDA		Mouse	MGI:MGI:4456947|PMID:15451416
Biological Process	GO:0006829	zinc ion transport	Slc30a1	IDA		Rat	PMID:7882967|RGD:61756
Biological Process	GO:0006829	zinc ion transport	Slc30a1	IMP		Rat	PMID:16741752|RGD:8554228

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern