Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC24A4
  • Mouse genes Slc24a4
  • Rat genes Slc24a4
  • Zfish genes slc24a4a,slc24a4b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc24a4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008273	calcium, potassium:sodium antiporter activity	SLC24A4	IDA		Human	PMID:26631410
Molecular Function	GO:0008273	calcium, potassium:sodium antiporter activity	Slc24a4	IDA		Mouse	MGI:MGI:6718234|PMID:27093457
Molecular Function	GO:0048306	calcium-dependent protein binding	Slc24a4	IPI	UniProtKB:P0DP27	Mouse	MGI:MGI:6716978|PMID:33199372
Molecular Function	GO:0005516	calmodulin binding	Slc24a4	IPI	UniProtKB:P0DP27	Mouse	MGI:MGI:6716978|PMID:33199372
Cellular Component	GO:0016324	apical plasma membrane	Slc24a4	IDA		Mouse	MGI:MGI:6716964|PMID:26403673
Cellular Component	GO:0016324	apical plasma membrane	Slc24a4	IDA		Mouse	MGI:MGI:6716966|PMID:27752731
Cellular Component	GO:0120199	cone photoreceptor outer segment	Slc24a4	IDA		Mouse	MGI:MGI:6116933|PMID:28650316
Cellular Component	GO:0120199	cone photoreceptor outer segment	slc24a4b	IGI	ZFIN:ZDB-GENE-050417-291	Zfish	PMID:28650316|ZFIN:ZDB-PUB-170627-5
Cellular Component	GO:0120199	cone photoreceptor outer segment	slc24a4a	IGI	ZFIN:ZDB-GENE-081031-75	Zfish	PMID:28650316|ZFIN:ZDB-PUB-170627-5
Cellular Component	GO:0005737	cytoplasm	Slc24a4	IDA		Mouse	MGI:MGI:5586774|PMID:24621671
Cellular Component	GO:0016020	membrane	Slc24a4	IDA		Mouse	MGI:MGI:6716978|PMID:33199372
Cellular Component	GO:0016020	membrane	Slc24a4	IDA		Mouse	MGI:MGI:5586774|PMID:24621671
Cellular Component	GO:0005886	plasma membrane	SLC24A4	IDA		Human	PMID:26631410
Cellular Component	GO:0005886	plasma membrane	Slc24a4	IDA		Mouse	MGI:MGI:6716968|PMID:29128492
Cellular Component	GO:0005886	plasma membrane	Slc24a4	IDA		Mouse	PMID:26247047
Cellular Component	GO:0005886	plasma membrane	Slc24a4	IDA		Rat	PMID:16617138|RGD:7175085
Cellular Component	GO:0031982	vesicle	Slc24a4	IDA		Mouse	MGI:MGI:6716978|PMID:33199372
Biological Process	GO:0097186	amelogenesis	Slc24a4	IMP		Mouse	MGI:MGI:5520028|PMID:23375655
Biological Process	GO:0097186	amelogenesis	Slc24a4	IMP		Mouse	MGI:MGI:6716966|PMID:27752731
Biological Process	GO:1990034	calcium ion export across plasma membrane	Slc24a4	IDA		Mouse	MGI:MGI:6716978|PMID:33199372
Biological Process	GO:0055074	calcium ion homeostasis	Slc24a4	IMP		Mouse	MGI:MGI:6716959|PMID:25096581
Biological Process	GO:0098703	calcium ion import across plasma membrane	Slc24a4	IDA		Mouse	MGI:MGI:6718234|PMID:27093457
Biological Process	GO:0070588	calcium ion transmembrane transport	SLC24A4	IDA		Human	PMID:26631410
Biological Process	GO:0071486	cellular response to high light intensity	Slc24a4	IMP		Mouse	MGI:MGI:6116933|PMID:28650316
Biological Process	GO:0036368	cone photoresponse recovery	Slc24a4	IMP		Mouse	MGI:MGI:6116933|PMID:28650316
Biological Process	GO:0050911	detection of chemical stimulus involved in sensory perception of smell	Slc24a4	IMP		Mouse	MGI:MGI:5817509|PMID:28053034
Biological Process	GO:0042756	drinking behavior	Slc24a4	IMP		Mouse	MGI:MGI:6716959|PMID:25096581
Biological Process	GO:0006874	intracellular calcium ion homeostasis	SLC24A4	IDA		Human	PMID:26631410
Biological Process	GO:0086009	membrane repolarization	Slc24a4	IMP		Mouse	MGI:MGI:5817509|PMID:28053034
Biological Process	GO:0050849	negative regulation of calcium-mediated signaling	Slc24a4	IDA		Mouse	MGI:MGI:6716978|PMID:33199372
Biological Process	GO:0021630	olfactory nerve maturation	Slc24a4	IMP		Mouse	MGI:MGI:5817509|PMID:28053034
Biological Process	GO:0007602	phototransduction	Slc24a4	IMP		Mouse	MGI:MGI:6116933|PMID:28650316
Biological Process	GO:0010628	positive regulation of gene expression	Slc24a4	IMP		Mouse	MGI:MGI:5817509|PMID:28053034
Biological Process	GO:0071805	potassium ion transmembrane transport	SLC24A4	IDA		Human	PMID:26631410
Biological Process	GO:1903998	regulation of eating behavior	Slc24a4	IMP		Mouse	MGI:MGI:6716959|PMID:25096581
Biological Process	GO:0008277	regulation of G protein-coupled receptor signaling pathway	Slc24a4	IMP	UniProtKB:P56450	Mouse	MGI:MGI:6716959|PMID:25096581
Biological Process	GO:0010469	regulation of signaling receptor activity	Slc24a4	IMP	UniProtKB:P56450	Mouse	MGI:MGI:6716959|PMID:25096581
Biological Process	GO:1990680	response to melanocyte-stimulating hormone	Slc24a4	IMP		Mouse	MGI:MGI:6716959|PMID:25096581
Biological Process	GO:1990834	response to odorant	Slc24a4	IMP		Mouse	MGI:MGI:5817509|PMID:28053034
Biological Process	GO:0007608	sensory perception of smell	Slc24a4	IMP		Mouse	MGI:MGI:5306100|PMID:22057188
Biological Process	GO:0035725	sodium ion transmembrane transport	SLC24A4	IDA		Human	PMID:26631410

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern