Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC22A8
  • Mouse genes Slc22a8
  • Rat genes Slc22a8
  • Zfish genes oatx
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc22a8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008514	organic anion transmembrane transporter activity	SLC22A8	IDA		Human	PMID:11907186
Molecular Function	GO:0008514	organic anion transmembrane transporter activity	Slc22a8	IDA		Rat	PMID:12679720|RGD:1299371
Molecular Function	GO:0008514	organic anion transmembrane transporter activity	oatx	IDA		Zfish	PMID:31255699
Molecular Function	GO:0015132	prostaglandin transmembrane transporter activity	SLC22A8	IDA		Human	PMID:11907186
Molecular Function	GO:0005080	protein kinase C binding	Slc22a8	IPI	RGD:3399	Rat	PMID:19028678|RGD:2317440
Molecular Function	GO:0015651	quaternary ammonium group transmembrane transporter activity	Slc22a8	IDA		Rat	PMID:17616214|RGD:1643126
Molecular Function	GO:0005452	solute:inorganic anion antiporter activity	SLC22A8	IDA		Human	PMID:15037815
Cellular Component	GO:0016324	apical plasma membrane	SLC22A8	IDA		Human	PMID:31791063
Cellular Component	GO:0016324	apical plasma membrane	Slc22a8	IDA		Rat	PMID:18619525|RGD:2301072
Cellular Component	GO:0016323	basolateral plasma membrane	SLC22A8	IDA		Human	PMID:15037815
Cellular Component	GO:0016323	basolateral plasma membrane	SLC22A8	IDA		Human	PMID:27053689
Cellular Component	GO:0016323	basolateral plasma membrane	SLC22A8	IDA		Human	PMID:31791063
Cellular Component	GO:0016323	basolateral plasma membrane	Slc22a8	IDA		Rat	PMID:17971680|RGD:2317443
Cellular Component	GO:0016323	basolateral plasma membrane	Slc22a8	IDA		Rat	PMID:18619525|RGD:2301072
Cellular Component	GO:0070062	extracellular exosome	SLC22A8	HDA		Human	PMID:19056867
Cellular Component	GO:0005886	plasma membrane	oatx	IDA		Zfish	PMID:31255699
Biological Process	GO:0034635	glutathione transport	Slc22a8	IDA		Rat	PMID:17719021|RGD:2317442
Biological Process	GO:0015732	prostaglandin transport	SLC22A8	IDA		Human	PMID:11907186
Biological Process	GO:0015697	quaternary ammonium group transport	Slc22a8	IDA		Rat	PMID:17616214|RGD:1643126
Biological Process	GO:0014070	response to organic cyclic compound	Slc22a8	IEP		Rat	PMID:16925582|RGD:1598604

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern