Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC22A13
  • Mouse genes Slc22a13
  • Rat genes Slc22a13,Slc22a13l1
  • Zfish genes slc22a13a,slc22a13b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc22a13

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0090416	nicotinate transmembrane transporter activity	SLC22A13	EXP		Human	PMID:18411268
Molecular Function	GO:0090416	nicotinate transmembrane transporter activity	SLC22A13	IDA		Human	PMID:18411268
Molecular Function	GO:0090416	nicotinate transmembrane transporter activity	SLC22A13	IDA		Human	PMID:35144162
Molecular Function	GO:0090416	nicotinate transmembrane transporter activity	Slc22a13	IDA		Mouse	MGI:MGI:7310370|PMID:35144162
Molecular Function	GO:0015143	urate transmembrane transporter activity	SLC22A13	IDA		Human	PMID:18411268
Molecular Function	GO:0015143	urate transmembrane transporter activity	SLC22A13	IDA		Human	PMID:35144162
Cellular Component	GO:0016324	apical plasma membrane	SLC22A13	IDA		Human	PMID:18411268
Cellular Component	GO:0005783	endoplasmic reticulum	SLC22A13	IDA		Human	PMID:19282870
Cellular Component	GO:0070062	extracellular exosome	SLC22A13	HDA		Human	PMID:19056867
Cellular Component	GO:0005794	Golgi apparatus	SLC22A13	IDA		Human	PMID:19282870
Cellular Component	GO:0005886	plasma membrane	SLC22A13	IDA		Human	PMID:19282870
Biological Process	GO:0045922	negative regulation of fatty acid metabolic process	SLC22A13	IDA		Human	PMID:24769897
Biological Process	GO:0045922	negative regulation of fatty acid metabolic process	Slc22a13	IDA		Mouse	MGI:MGI:6212098|PMID:24769897
Biological Process	GO:2001142	nicotinate transport	SLC22A13	IDA		Human	PMID:18411268
Biological Process	GO:2001142	nicotinate transport	SLC22A13	IDA		Human	PMID:35144162
Biological Process	GO:2001142	nicotinate transport	Slc22a13	IDA		Mouse	MGI:MGI:7310370|PMID:35144162
Biological Process	GO:0002854	positive regulation of T cell mediated cytotoxicity directed against tumor cell target	SLC22A13	IDA		Human	PMID:19282870
Biological Process	GO:0015747	urate transport	SLC22A13	IDA		Human	PMID:18411268
Biological Process	GO:0015747	urate transport	SLC22A13	IDA		Human	PMID:35144162

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern