Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC1A7
  • Mouse genes Slc1a7
  • Rat genes Slc1a7
  • Zfish genes slc1a7a,slc1a7b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc1a7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008068	extracellularly glutamate-gated chloride channel activity	Slc1a7	IDA		Mouse	MGI:MGI:7310191|PMID:16973698
Molecular Function	GO:0008068	extracellularly glutamate-gated chloride channel activity	Slc1a7	IDA		Mouse	MGI:MGI:7294459|PMID:32233906
Molecular Function	GO:0015501	glutamate:sodium symporter activity	SLC1A7	IDA		Human	PMID:9108121
Molecular Function	GO:0015501	glutamate:sodium symporter activity	Slc1a7	IDA		Mouse	MGI:MGI:7294459|PMID:32233906
Molecular Function	GO:0015501	glutamate:sodium symporter activity	Slc1a7	IDA		Mouse	MGI:MGI:7310191|PMID:16973698
Molecular Function	GO:0005313	L-glutamate transmembrane transporter activity	Slc1a7	IDA		Mouse	PMID:24307171
Molecular Function	GO:0008509	monoatomic anion transmembrane transporter activity	Slc1a7	IDA		Mouse	PMID:24307171
Cellular Component	GO:0043679	axon terminus	Slc1a7	IDA		Mouse	MGI:MGI:7310191|PMID:16973698
Cellular Component	GO:0098978	glutamatergic synapse	Slc1a7	IDA		Mouse	PMID:23049999
Cellular Component	GO:1990796	photoreceptor cell terminal bouton	Slc1a7	IDA		Mouse	MGI:MGI:7310191|PMID:16973698
Cellular Component	GO:0005886	plasma membrane	Slc1a7	IDA		Mouse	PMID:24307171
Cellular Component	GO:0045211	postsynaptic membrane	Slc1a7	IDA		Mouse	PMID:23049999
Cellular Component	GO:0042734	presynaptic membrane	Slc1a7	IDA		Mouse	PMID:23049999
Biological Process	GO:1902476	chloride transmembrane transport	Slc1a7	IDA		Mouse	MGI:MGI:7294459|PMID:32233906
Biological Process	GO:0015813	L-glutamate transmembrane transport	Slc1a7	IDA		Mouse	MGI:MGI:7310191|PMID:16973698
Biological Process	GO:0015813	L-glutamate transmembrane transport	Slc1a7	IDA		Mouse	MGI:MGI:7294459|PMID:32233906
Biological Process	GO:0015813	L-glutamate transmembrane transport	Slc1a7	IDA		Mouse	PMID:24307171
Biological Process	GO:0098656	monoatomic anion transmembrane transport	Slc1a7	IDA		Mouse	PMID:24307171
Biological Process	GO:0001504	neurotransmitter uptake	SLC1A7	IDA		Human	PMID:9108121
Biological Process	GO:0001504	neurotransmitter uptake	SLC1A7	IMP		Human	PMID:9108121

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern