Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC1A5
  • Mouse genes Slc1a5
  • Rat genes Slc1a5
  • Zfish genes slc1a5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc1a5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015183	L-aspartate transmembrane transporter activity	Slc1a5	IDA		Mouse	MGI:MGI:6393124|PMID:14622120
Molecular Function	GO:0015183	L-aspartate transmembrane transporter activity	Slc1a5	IDA		Rat	PMID:14622120|RGD:21201277
Molecular Function	GO:0015186	L-glutamine transmembrane transporter activity	SLC1A5	IDA		Human	PMID:29872227
Molecular Function	GO:0015194	L-serine transmembrane transporter activity	Slc1a5	IDA		Rat	PMID:12885409|RGD:1642943
Molecular Function	GO:0015175	neutral L-amino acid transmembrane transporter activity	Slc1a5	IDA		Mouse	PMID:10933718
Molecular Function	GO:0005515	protein binding	SLC1A5	IPI	UniProtKB:M5A8F1	Human	PMID:23492904
Molecular Function	GO:0005515	protein binding	SLC1A5	IPI	UniProtKB:Q99942	Human	PMID:25759021
Molecular Function	GO:0005515	protein binding	SLC1A5	IPI	UniProtKB:A5PKU2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC1A5	IPI	UniProtKB:O95236-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC1A5	IPI	UniProtKB:P60201-2	Human	PMID:32296183
Cellular Component	GO:0009925	basal plasma membrane	Slc1a5	IDA		Mouse	MGI:MGI:6393124|PMID:14622120
Cellular Component	GO:0070062	extracellular exosome	SLC1A5	HDA		Human	PMID:20458337
Cellular Component	GO:0016020	membrane	SLC1A5	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	SLC1A5	IDA		Human	PMID:29872227
Cellular Component	GO:0005886	plasma membrane	SLC1A5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	SLC1A5	IDA		Human	PMID:23492904
Cellular Component	GO:0005886	plasma membrane	Slc1a5	IDA		Mouse	MGI:MGI:6393124|PMID:14622120
Biological Process	GO:0003333	amino acid transmembrane transport	Slc1a5	IDA		Mouse	MGI:MGI:1933956|PMID:10933718
Biological Process	GO:0010585	glutamine secretion	Slc1a5	IDA		Rat	PMID:10537079|RGD:1299491
Biological Process	GO:0006868	glutamine transport	SLC1A5	IDA		Human	PMID:29872227
Biological Process	GO:0140009	L-aspartate import across plasma membrane	Slc1a5	IDA		Mouse	MGI:MGI:6393124|PMID:14622120
Biological Process	GO:0140009	L-aspartate import across plasma membrane	Slc1a5	IDA		Rat	PMID:14622120|RGD:21201277
Biological Process	GO:1903803	L-glutamine import across plasma membrane	Slc1a5	IDA		Rat	PMID:10537079|RGD:1299491
Biological Process	GO:0015825	L-serine transport	Slc1a5	IDA		Rat	PMID:12885409|RGD:1642943
Biological Process	GO:0015804	neutral amino acid transport	Slc1a5	IDA		Mouse	MGI:MGI:1933956|PMID:10933718
Biological Process	GO:0070207	protein homotrimerization	SLC1A5	IDA		Human	PMID:29872227
Biological Process	GO:0150104	transport across blood-brain barrier	Slc1a5	IDA		Mouse	MGI:MGI:6393124|PMID:14622120

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern