Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC1A4
  • Mouse genes Slc1a4
  • Rat genes Slc1a4
  • Zfish genes slc1a4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc1a4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005254	chloride channel activity	SLC1A4	IDA		Human	PMID:8910405
Molecular Function	GO:0015180	L-alanine transmembrane transporter activity	SLC1A4	IMP		Human	PMID:26041762
Molecular Function	GO:0015180	L-alanine transmembrane transporter activity	SLC1A4	IDA		Human	PMID:8101838
Molecular Function	GO:0015180	L-alanine transmembrane transporter activity	SLC1A4	IDA		Human	PMID:8340364
Molecular Function	GO:0015180	L-alanine transmembrane transporter activity	SLC1A4	IDA		Human	PMID:8910405
Molecular Function	GO:0015183	L-aspartate transmembrane transporter activity	Slc1a4	IDA		Mouse	MGI:MGI:6393124|PMID:14622120
Molecular Function	GO:0015184	L-cystine transmembrane transporter activity	SLC1A4	IDA		Human	PMID:8101838
Molecular Function	GO:0015184	L-cystine transmembrane transporter activity	SLC1A4	IDA		Human	PMID:8910405
Molecular Function	GO:0034590	L-hydroxyproline transmembrane transporter activity	SLC1A4	IDA		Human	PMID:14502423
Molecular Function	GO:0015193	L-proline transmembrane transporter activity	SLC1A4	IDA		Human	PMID:14502423
Molecular Function	GO:0015194	L-serine transmembrane transporter activity	SLC1A4	IMP		Human	PMID:26041762
Molecular Function	GO:0015194	L-serine transmembrane transporter activity	SLC1A4	IDA		Human	PMID:8101838
Molecular Function	GO:0015194	L-serine transmembrane transporter activity	SLC1A4	IDA		Human	PMID:8340364
Molecular Function	GO:0015194	L-serine transmembrane transporter activity	SLC1A4	IDA		Human	PMID:8910405
Molecular Function	GO:0015194	L-serine transmembrane transporter activity	Slc1a4	IDA		Mouse	PMID:11030592
Molecular Function	GO:0015194	L-serine transmembrane transporter activity	Slc1a4	IDA		Rat	PMID:12885409|RGD:1642943
Molecular Function	GO:0015194	L-serine transmembrane transporter activity	Slc1a4	IMP		Rat	PMID:15099708|RGD:1302759
Molecular Function	GO:0015195	L-threonine transmembrane transporter activity	SLC1A4	IDA		Human	PMID:8340364
Molecular Function	GO:0015175	neutral L-amino acid transmembrane transporter activity	Slc1a4	IDA		Mouse	PMID:10933718
Cellular Component	GO:0009986	cell surface	SLC1A4	HDA		Human	PMID:19581412
Cellular Component	GO:0005813	centrosome	SLC1A4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030425	dendrite	Slc1a4	IDA		Rat	PMID:11675121|RGD:1642942
Cellular Component	GO:0070062	extracellular exosome	SLC1A4	HDA		Human	PMID:20458337
Cellular Component	GO:0005882	intermediate filament	Slc1a4	IDA		Mouse	PMID:12533615
Cellular Component	GO:0016020	membrane	SLC1A4	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	SLC1A4	IDA		Human	PMID:26041762
Cellular Component	GO:0043025	neuronal cell body	Slc1a4	IDA		Rat	PMID:11675121|RGD:1642942
Cellular Component	GO:0005886	plasma membrane	SLC1A4	IMP		Human	PMID:26041762
Biological Process	GO:0050890	cognition	SLC1A4	IMP		Human	PMID:16897601
Biological Process	GO:0034589	hydroxyproline transport	SLC1A4	IDA		Human	PMID:14502423
Biological Process	GO:1904273	L-alanine import across plasma membrane	SLC1A4	IMP		Human	PMID:26041762
Biological Process	GO:0015808	L-alanine transport	SLC1A4	IDA		Human	PMID:8101838
Biological Process	GO:0015808	L-alanine transport	SLC1A4	IDA		Human	PMID:8340364
Biological Process	GO:0015808	L-alanine transport	SLC1A4	IDA		Human	PMID:8910405
Biological Process	GO:0140009	L-aspartate import across plasma membrane	Slc1a4	IDA		Mouse	MGI:MGI:6393124|PMID:14622120
Biological Process	GO:0015811	L-cystine transport	SLC1A4	IDA		Human	PMID:8101838
Biological Process	GO:0015811	L-cystine transport	SLC1A4	IDA		Human	PMID:8910405
Biological Process	GO:1903812	L-serine import across plasma membrane	SLC1A4	IMP		Human	PMID:26041762
Biological Process	GO:0015825	L-serine transport	SLC1A4	IDA		Human	PMID:8101838
Biological Process	GO:0015825	L-serine transport	SLC1A4	IDA		Human	PMID:8340364
Biological Process	GO:0015825	L-serine transport	SLC1A4	IDA		Human	PMID:8910405
Biological Process	GO:0015825	L-serine transport	Slc1a4	IDA		Rat	PMID:12885409|RGD:1642943
Biological Process	GO:0015825	L-serine transport	Slc1a4	IMP		Rat	PMID:15099708|RGD:1302759
Biological Process	GO:0015824	proline transport	SLC1A4	IDA		Human	PMID:14502423
Biological Process	GO:0098718	serine import across plasma membrane	Slc1a4	IDA		Mouse	PMID:11030592
Biological Process	GO:0015826	threonine transport	SLC1A4	IDA		Human	PMID:8340364

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern