Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC12A7
  • Mouse genes Slc12a7
  • Rat genes Slc12a7
  • Zfish genes slc12a7a,slc12a7b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc12a7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008519	ammonium transmembrane transporter activity	Slc12a7	IDA		Mouse	MGI:MGI:6393154|PMID:12657561
Molecular Function	GO:0015379	potassium:chloride symporter activity	Slc12a7	IDA		Mouse	MGI:MGI:2384257|PMID:12106695
Molecular Function	GO:0015379	potassium:chloride symporter activity	Slc12a7	IDA		Mouse	MGI:MGI:7327240|PMID:11551954
Molecular Function	GO:0019901	protein kinase binding	SLC12A7	IPI	UniProtKB:Q9UEW8	Human	PMID:24393035
Cellular Component	GO:0032991	protein-containing complex	SLC12A7	IDA		Human	PMID:28246125
Biological Process	GO:0140157	ammonium import across plasma membrane	Slc12a7	IDA		Mouse	MGI:MGI:6393154|PMID:12657561
Biological Process	GO:0006884	cell volume homeostasis	Slc12a7	IMP		Rat	PMID:15533301|RGD:1558104
Biological Process	GO:0071333	cellular response to glucose stimulus	Slc12a7	IDA		Mouse	PMID:24089410
Biological Process	GO:0071805	potassium ion transmembrane transport	Slc12a7	IDA		Mouse	MGI:MGI:7327240|PMID:11551954

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern