Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC12A4
  • Mouse genes Slc12a4
  • Rat genes Slc12a4
  • Zfish genes slc12a4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc12a4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	SLC12A4	IDA		Human	PMID:34031912
Molecular Function	GO:0015379	potassium:chloride symporter activity	SLC12A4	IDA		Human	PMID:34031912
Molecular Function	GO:0015379	potassium:chloride symporter activity	Slc12a4	IDA		Mouse	MGI:MGI:7327240|PMID:11551954
Molecular Function	GO:0005515	protein binding	SLC12A4	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC12A4	IPI	UniProtKB:P59991	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC12A4	IPI	UniProtKB:Q3LHN2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC12A4	IPI	UniProtKB:Q8IYB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC12A4	IPI	UniProtKB:Q8N720	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC12A4	IPI	UniProtKB:Q8N9M5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC12A4	IPI	UniProtKB:Q9BYD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC12A4	IPI	UniProtKB:Q9Y2T2	Human	PMID:32296183
Molecular Function	GO:0019901	protein kinase binding	SLC12A4	IPI	UniProtKB:O95747	Human	PMID:24393035
Molecular Function	GO:0019901	protein kinase binding	SLC12A4	IPI	UniProtKB:Q9UEW8	Human	PMID:24393035
Cellular Component	GO:0005765	lysosomal membrane	SLC12A4	HDA		Human	PMID:17897319
Biological Process	GO:0071805	potassium ion transmembrane transport	Slc12a4	IDA		Mouse	MGI:MGI:7327240|PMID:11551954

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern