Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLA2
  • Mouse genes Sla2
  • Rat genes Sla2
  • Zfish genes sla2a,sla2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sla2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SLA2	IPI	UniProtKB:P20963	Human	PMID:11891219
Molecular Function	GO:0005515	protein binding	SLA2	IPI	UniProtKB:P22681	Human	PMID:11891219
Molecular Function	GO:0005515	protein binding	SLA2	IPI	UniProtKB:P43403	Human	PMID:11891219
Molecular Function	GO:0005515	protein binding	SLA2	IPI	UniProtKB:P04626	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	SLA2	IPI	UniProtKB:P08581	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	SLA2	IPI	UniProtKB:P10721	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	SLA2	IPI	UniProtKB:Q13480	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	SLA2	IPI	UniProtKB:P54646	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLA2	IPI	UniProtKB:P57075-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Sla2	IPI	UniProtKB:P36888	Mouse	MGI:MGI:6272221|PMID:27458164
Molecular Function	GO:0005515	protein binding	Sla2	IPI	UniProtKB:Q9ULV8	Mouse	PMID:12024036
Molecular Function	GO:0005515	protein binding	Sla2	IPI	UniProtKB:P20963	Mouse	PMID:11891219
Molecular Function	GO:0005515	protein binding	Sla2	IPI	UniProtKB:P43403	Mouse	PMID:12024036
Molecular Function	GO:0005515	protein binding	Sla2	IPI	UniProtKB:P43403	Mouse	PMID:11891219
Molecular Function	GO:0035591	signaling adaptor activity	SLA2	IDA		Human	PMID:11891219
Cellular Component	GO:0031410	cytoplasmic vesicle	Sla2	IDA		Mouse	PMID:12024036
Cellular Component	GO:0005794	Golgi apparatus	SLA2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	SLA2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005770	late endosome	Sla2	IDA		Mouse	PMID:12024036
Cellular Component	GO:0005654	nucleoplasm	SLA2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Sla2	IDA		Mouse	PMID:12024036
Biological Process	GO:0050849	negative regulation of calcium-mediated signaling	SLA2	IDA		Human	PMID:11696592
Biological Process	GO:0050860	negative regulation of T cell receptor signaling pathway	SLA2	IMP		Human	PMID:11891219
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	SLA2	IDA		Human	PMID:11696592
Biological Process	GO:0042110	T cell activation	SLA2	IDA		Human	PMID:11891219
Biological Process	GO:0042110	T cell activation	Sla2	IDA		Mouse	PMID:12024036
Biological Process	GO:0042110	T cell activation	Sla2	IDA		Mouse	PMID:11891219

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern