Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SHLD2
  • Mouse genes Shld2
  • Rat genes Shld2
  • Zfish genes shld2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Shld2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SHLD2	IPI	UniProtKB:Q6ZNX1	Human	PMID:29656893
Molecular Function	GO:0005515	protein binding	SHLD2	IPI	UniProtKB:Q8IYI0	Human	PMID:29656893
Molecular Function	GO:0005515	protein binding	SHLD2	IPI	UniProtKB:Q9UI95	Human	PMID:29656893
Molecular Function	GO:0005515	protein binding	SHLD2	IPI	UniProtKB:Q12888	Human	PMID:29789392
Molecular Function	GO:0005515	protein binding	SHLD2	IPI	UniProtKB:Q5UIP0	Human	PMID:29789392
Molecular Function	GO:0005515	protein binding	SHLD2	IPI	UniProtKB:Q9UI95	Human	PMID:29789392
Cellular Component	GO:0015629	actin cytoskeleton	SHLD2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005694	chromosome	SHLD2	IDA		Human	PMID:29656893
Cellular Component	GO:0005654	nucleoplasm	SHLD2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SHLD2	IDA		Human	PMID:29789392
Cellular Component	GO:0035861	site of double-strand break	SHLD2	IDA		Human	PMID:29656893
Biological Process	GO:2000042	negative regulation of double-strand break repair via homologous recombination	SHLD2	IDA		Human	PMID:29656893
Biological Process	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	SHLD2	IDA		Human	PMID:29656893
Biological Process	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	SHLD2	IDA		Human	PMID:29789392
Biological Process	GO:0045830	positive regulation of isotype switching	SHLD2	IDA		Human	PMID:29656893

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern